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Unilateral Versus Bilateral Antegrade Cerebral Protection During Aortic Surgery: An Updated Meta-Analysis  Emiliano Angeloni, MD, Giovanni Melina, PhD,

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Presentation on theme: "Unilateral Versus Bilateral Antegrade Cerebral Protection During Aortic Surgery: An Updated Meta-Analysis  Emiliano Angeloni, MD, Giovanni Melina, PhD,"— Presentation transcript:

1 Unilateral Versus Bilateral Antegrade Cerebral Protection During Aortic Surgery: An Updated Meta-Analysis  Emiliano Angeloni, MD, Giovanni Melina, PhD, Simone K. Refice, MD, Antonino Roscitano, MD, Fabio Capuano, PhD, Cosimo Comito, MD, Riccardo Sinatra, MD  The Annals of Thoracic Surgery  Volume 99, Issue 6, Pages (June 2015) DOI: /j.athoracsur Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Meta-analysis of postoperative mortality. (bASCP = bilateral antegrade selective cerebral perfusion; CI = confidence interval; uASCP = unilateral antegrade selective cerebral perfusion.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 Meta-analysis of postoperative permanent neurologic disease (PND). (bASCP = bilateral antegrade selective cerebral perfusion; CI = confidence interval; uASCP = unilateral antegrade selective cerebral perfusion.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

4 Fig 3 Meta-regression analysis of time of circulatory arrest (minutes) on mortality rates for (A) bilateral and (B) unilateral antegrade selective cerebral perfusion. (CA = circulatory arrest; b-ASCP = bilateral antegrade selective cerebral perfusion; u-ASCP = unilateral antegrade selective cerebral perfusion.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

5 Fig 4 Meta-regression analysis of time of circulatory arrest (minutes) on (A) permanent neurologic dysfunction (PND), and (B) temporary neurologic dysfunction (TND) rates in the overall study population. (CA = circulatory arrest.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

6 Fig 5 Meta-regression analysis of temperature of circulatory arrest (°C) on (A) mortality, (B) permanent neurologic dysfunction (PND), and (C) temporary neurologic dysfunction (TND) rates in the overall study population. (CA = circulatory arrest.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

7 Fig 6 Meta-regression analysis of sample size on mortality (A) mortality, (B) permanent neurologic dysfunction (PND), and (C) temporary neurologic dysfunction (TND) rates in the overall study population. (SS = sample size.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

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