1. The Blood System

2. Blood Vessels

3. Arteries have muscle and elastic fibers in their walls
Arteries have muscle and elastic fibers in their walls. The muscle and elastic fibers assist in maintaining blood pressure between pump cycles.

4. Blood flows through tissues in capillaries with permeable walls that allow exchange of materials between cells in the tissue and the blood in the capillaries.

5. Valves in veins and the heart ensure circulation of blood by preventing backflow.

6. There is a separate circulation for the lungs

7. Arteries convey blood at high pressure from the ventricles to the tissues of the body. Veins collect blood at low pressure from the tissues of the body and return it to the atria of the heart.

8. -The heart beat is initiated by a group of specialized muscle cells in the right atrium called the sinoatrial node. -The sinoatrial node acts as a pacemaker.

9. The sinoatrial node sends an electrical signal that stimulates contraction as it is propagated through the walls of the atria and then the walls of the ventricles.

10. The heart rate can be increased or decreased by impulses brought to the heart through two nerves from the medulla of the brain. Epinephrine increases the heart rate to prepare for vigorous physical activity.

11. Skills, Applications, and Nature of Science

12. Pressure changes in the left atrium, left ventricle and aorta during the cardiac cycle.
Atrial systole
Both atria contract and push stored blood across AV valves into ventricles, to help fill them
Reduces the volume of atria and increases pressure
Ventricular systole
After atria contracts, ventricles begin to contract
Pressure in ventricles increases, blood is forced against AV valves
Valves close to prevent backflow
Volume is reduced
Blood is ejected into arteries under high pressure through aortic and pulmonary valves
Ventricular diastole
End of cardiac cycle, all chambers relax
Aortic and pulmonary valves close / prevents backflow into heart
Atria begin to fill up again to start next cycle
Volume increases and pressure decreases in ventricle

13. William Harvey’s discovery of the circulation of the blood with the heart acting as the pump. NATURE OF SCIENCE: Theories are regarded as uncertain- William Harvey overturned theories developed by the ancient Greek philosopher Galen on movement of blood in the body.

14. Causes and consequences of occlusions of the coronary arteries
Coronary artery disease is thought to begin with damage or injury to the inner layer of a coronary artery, sometimes as early as childhood. The damage may be caused by various factors, including:
Smoking
High blood pressure
High cholesterol
Diabetes or insulin resistance
Radiation therapy to the chest, as used for certain types of cancer
Sedentary lifestyle