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Assessment of Fibrosis by Transient Elastography Compared With Liver Biopsy and Morphometry in Chronic Liver Diseases  Grace Lai–Hung Wong, Vincent Wai–Sun.

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Presentation on theme: "Assessment of Fibrosis by Transient Elastography Compared With Liver Biopsy and Morphometry in Chronic Liver Diseases  Grace Lai–Hung Wong, Vincent Wai–Sun."— Presentation transcript:

1 Assessment of Fibrosis by Transient Elastography Compared With Liver Biopsy and Morphometry in Chronic Liver Diseases  Grace Lai–Hung Wong, Vincent Wai–Sun Wong, Paul Cheung–Lung Choi, Anthony Wing–Hung Chan, Richard Hoi–Leong Chum, Henry Kai–Wing Chan, Kenneth Ka–Ki Lau, Angel Mei–Ling Chim, Karen Ka–Lam Yiu, Francis Ka–Leung Chan, Joseph Jao–Yao Sung, Henry Lik–Yuen Chan  Clinical Gastroenterology and Hepatology  Volume 6, Issue 9, Pages (September 2008) DOI: /j.cgh Copyright © 2008 AGA Institute Terms and Conditions

2 Figure 1 Scatter plots of the relationship between areas of fibrosis and LSMs in different regions: (A) Pericellular region (r = 0.43, P < .001); (B) perivenular region (r = 0.21, P = .026); (C) periportal region (r = 0.25, P = .007); and (D) overall fibrosis (r = 0.32, P = .001). Clinical Gastroenterology and Hepatology 2008 6, DOI: ( /j.cgh ) Copyright © 2008 AGA Institute Terms and Conditions

3 Figure 2 Liver stiffness values for each fibrosis stage (0–4) in patients with (A) viral hepatitis and (B) NAFLD. Top and bottom of the boxes are the first and third quartiles. Length of the box represents interquartile ranges, within which are located 50% of the values. Lines through the middle of the boxes represent median values. Clinical Gastroenterology and Hepatology 2008 6, DOI: ( /j.cgh ) Copyright © 2008 AGA Institute Terms and Conditions

4 Figure 3 ROC curves of LSMs for (A) bridging fibrosis (area under curve [AUC], 0.87; 95% CI, 0.81–0.93; P < .001) and (B) liver cirrhosis (AUC, 0.89; 95% CI, 0.83–0.94; P < .001). Clinical Gastroenterology and Hepatology 2008 6, DOI: ( /j.cgh ) Copyright © 2008 AGA Institute Terms and Conditions


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