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Refinement of survival prediction in patients undergoing lower extremity bypass surgery: Stratification by chronic kidney disease classification  Christopher.

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Presentation on theme: "Refinement of survival prediction in patients undergoing lower extremity bypass surgery: Stratification by chronic kidney disease classification  Christopher."— Presentation transcript:

1 Refinement of survival prediction in patients undergoing lower extremity bypass surgery: Stratification by chronic kidney disease classification  Christopher D. Owens, MD, Karen J. Ho, MD, Sang Kim, BS, Andres Schanzer, MD, Julie Lin, MD, MPH, Evan Matros, MD, Michael Belkin, MD, Michael S. Conte, MD  Journal of Vascular Surgery  Volume 45, Issue 5, Pages (May 2007) DOI: /j.jvs Copyright © 2007 The Society for Vascular Surgery Terms and Conditions

2 Fig 1 A, Scatter plot shows the distribution of preoperative serum creatinine concentration within each stage of chronic kidney disease (CKD) based on kidney function as determined by the estimated glomerular filtration rate (eGFR), with each point representing a single patient and distribution of eGFR. B, Comparison of Cockroft-Gault equations and Modified Diet in Renal Disease formula (MDRD) for eGFR. Age, years; weight, kg; and serum creatinine, mg/dL. Estimated GFR is calculated by the MDRD formula. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2007 The Society for Vascular Surgery Terms and Conditions

3 Fig 2 A, Indication for lower extremity bypass and B, site of distal anastomosis by chronic kidney disease (CKD) stage, expressed as a percentage of total patients. Pop, Popliteal artery; tibial, anterior or posterior tibial artery or peroneal artery; pedal, pedal or plantar artery. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2007 The Society for Vascular Surgery Terms and Conditions

4 Fig 3 Kaplan-Meier estimates of overall survival by (A) chronic kidney disease (CKD) classification and (B) estimated glomerular filtration rate (eGFR). Kaplan-Meier estimates of amputation-free survival by (C) CKD classification (D) and eGFR. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2007 The Society for Vascular Surgery Terms and Conditions

5 Fig 4 A, The risk of mortality and the B, combined end point of death and amputation by chronic kidney disease (CKD) stage after 5 years. Hazard ratios and 95% confidence intervals are shown. †CKD 1, or GFR >90 mL/(min·1.73 m2) is the referent. ‡MV, multivariable. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2007 The Society for Vascular Surgery Terms and Conditions

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