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Localized cutaneous argyria

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1 Localized cutaneous argyria
Alexandra C. Hristov, MD, Whitney A. High, MD, JD, Loren E. Golitz, MD  Journal of the American Academy of Dermatology  Volume 65, Issue 3, Pages (September 2011) DOI: /j.jaad Copyright © 2010 American Academy of Dermatology, Inc. Terms and Conditions

2 Fig 1 Brown-black granules coat dermal elastic and collagen fibers (A) and basement membrane of eccrine sweat glands (B). An adjacent ill-defined aggregate of histiocytes contains numerous crystalline, silica fragments (C). (Hematoxylin-eosin stain; original magnification: A, B, and C ×600.) Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2010 American Academy of Dermatology, Inc. Terms and Conditions

3 Fig 2 A, Dark field microscopy reveals small, white, refractile granules deposited on elastic and collagen fibers. B, Scanning electron microscopy demonstrates small particles on elastic and collagen fibers. C, Energy-dispersive spectroscopy identifies the particles as minute fragments of silver and copper and confirms admixed silica. (A, Hematoxylin-eosin stain; B and C, unstained slides; original magnifications: A, ×400; B, ×1500.) Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2010 American Academy of Dermatology, Inc. Terms and Conditions


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