1. Prospective Cohort Study of Body Image Disturbance in Surgically-Managed Head and Neck Cancer Patients
Evan Graboyes MD
Department of Otolaryngology-Head & Neck Surgery
Cancer Control Program, Hollings Cancer Center
Medical University of South Carolina

2. HNC arises in cosmetically + functionally
Background: Exposure
HNC arises in cosmetically + functionally
 highly visible, socially significant changes
Significant psychosocial morbidity
Depression
Occurs in 50% of HN patients during Rx
Suicide
2x increased adjusted odds vs any other cancer
Lydiatt et al. JAMA Oto-HNS 2014
Osazuwa-Peters et al. Cancer 2018

3. Body Image Disturbance
Background: Outcome
Body Image Disturbance
multi-D phenom of self-perceived change in appearance and/or function
Common: up to 75% of HNC pts
Significant psychosocial impairment
Assessed using PROMs
Rhoten et al. Oral Oncol 2013
Graboyes et al. OtoHNS 2018

4. Study Question/Hypothesis
Prior studies w/ cross sectional design
Uncertain risk factors for BID prevents targeting of prevention and treatment strategies
Hypothesis: Baseline (pre-treatment) depression predicts development of post-treatment BID

5. Study Design and Population
Design: Prospective cohort study
Inclusion Criteria
> 18 years of age
SCC of OC, OP, HP, Lx or cutaneous malignancy of HN
Surgery at MUSC+/- reconstruction +/- adjuvant therapy
Exposure Status
Baseline (Pre-treatment) Depression vs No-Depression

6. Methods: Exposure, Covariates, Outcome
Depression
Covariates
Sociodemographics and severity of comorbidity
Oncologic + treatment characteristics
PROMIS: Satisfaction w/ roles, social isolation
Shame and Stigma Scale
Performance Status Scale-HN
Primary Outcome Measure
Body Image Scale

7. Thank you