Presentation is loading. Please wait.

Presentation is loading. Please wait.

Impact of Polymorphic Variations of Gemcitabine Metabolism, DNA Damage Repair, and Drug-Resistance Genes on the Effect of High-Dose Chemotherapy for Relapsed.

Similar presentations


Presentation on theme: "Impact of Polymorphic Variations of Gemcitabine Metabolism, DNA Damage Repair, and Drug-Resistance Genes on the Effect of High-Dose Chemotherapy for Relapsed."— Presentation transcript:

1 Impact of Polymorphic Variations of Gemcitabine Metabolism, DNA Damage Repair, and Drug-Resistance Genes on the Effect of High-Dose Chemotherapy for Relapsed or Refractory Lymphoid Malignancies  Keiji Shinozuka, Hongwei Tang, Roy B. Jones, Donghui Li, Yago Nieto  Biology of Blood and Marrow Transplantation  Volume 22, Issue 5, Pages (May 2016) DOI: /j.bbmt Copyright © 2016 American Society for Blood and Marrow Transplantation Terms and Conditions

2 Figure 1 Kaplan-Meier plot of overall survival (A) and progression-free survival (B) by risk score in the entire study population. The number 0 or 1 in panel A indicates the absence or presence of the at-risk TT genotype of TREX1 Ex (rs11797), respectively. The numbers 0 to 2 in panel B indicate the number of at-risk genotypes of MRP2 Ex10 + 40GG/GA and MLH1 IVS12-169 TT genotypes. The 3 lines for each genotype represent the survival curve and their 95% confidence intervals. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2016 American Society for Blood and Marrow Transplantation Terms and Conditions


Download ppt "Impact of Polymorphic Variations of Gemcitabine Metabolism, DNA Damage Repair, and Drug-Resistance Genes on the Effect of High-Dose Chemotherapy for Relapsed."

Similar presentations


Ads by Google