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Small but Mighty: Nanoparticles Probe Cellular Signaling Pathways

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Presentation on theme: "Small but Mighty: Nanoparticles Probe Cellular Signaling Pathways"— Presentation transcript:

1 Small but Mighty: Nanoparticles Probe Cellular Signaling Pathways
Darren Yang, Wesley P. Wong  Developmental Cell  Volume 37, Issue 5, Pages (June 2016) DOI: /j.devcel Copyright © 2016 Elsevier Inc. Terms and Conditions

2 Figure 1 Mechanically Probing Cell-Signaling Pathways with Magnetoplasmonic Nanoparticles Conventional micron-size probes can form multivalent interactions with cell surface receptors, perturbing cellular structure and immobilizing receptors, whereas magnetoplasmonic nanoparticles (MPNs) have the ability to bind monovalently (one-to-one), providing precise chemical and physical control of ligand-receptor binding. In the presence of a magnetic field, the MPNs can spatially localize and apply controlled mechanical forces to the targeted receptors. Developmental Cell  , DOI: ( /j.devcel ) Copyright © 2016 Elsevier Inc. Terms and Conditions

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