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Dana Amiraian, Joseph Cernigliaro, Qihui “Jim” Zhai, Steven Petrou 

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Presentation on theme: "Dana Amiraian, Joseph Cernigliaro, Qihui “Jim” Zhai, Steven Petrou "— Presentation transcript:

1 Primary malignant melanoma of the female urethra: A radiologic–pathologic correlation 
Dana Amiraian, Joseph Cernigliaro, Qihui “Jim” Zhai, Steven Petrou  Cancer Treatment and Research Communications  Volume 3, Pages (January 2015) DOI: /j.ctrc Copyright © 2015 The Authors Terms and Conditions

2 Figure 1 Round, circumscribed, isointense urethral mass on coronal T2 MRI. Cancer Treatment and Research Communications 2015 3, 13-16DOI: ( /j.ctrc ) Copyright © 2015 The Authors Terms and Conditions

3 Figure 2 Round, circumscribed, isointense posterior urethral mass with mass effect on the vagina on sagittal T2 MRI. Cancer Treatment and Research Communications 2015 3, 13-16DOI: ( /j.ctrc ) Copyright © 2015 The Authors Terms and Conditions

4 Figure 3 Urethral mass without hyperintensity on coronal T1 MRI.
Cancer Treatment and Research Communications 2015 3, 13-16DOI: ( /j.ctrc ) Copyright © 2015 The Authors Terms and Conditions

5 Figure 4 Round, circumscribed, enhancing posterior urethral mass with mass effect on the vagina on sagittal post-contrast fat-saturated MRI. Cancer Treatment and Research Communications 2015 3, 13-16DOI: ( /j.ctrc ) Copyright © 2015 The Authors Terms and Conditions

6 Figure 5 (A) Urothelial epithelium underwent squamous metaplasia. Brown melanin-containing tumor cells with pagetoid spreading pattern, occasionally spreading into top of epithelium. No invasive component within this focus. (B) Urothelial epithelium underwent squamous metaplasia. Brown melanin pigment within tumor cytoplasm is identified. Melanoma tumor cells appear to arise from basal epithelium and invade downward beyond epithelium. (C) Higher power of figure B shows brown melanin pigment within invasive tumor cell cytoplasm. Basal in situ component is present on left of image. (D) Numerous mitoses along with scattered brown melanin-containing tumor cells. Cancer Treatment and Research Communications 2015 3, 13-16DOI: ( /j.ctrc ) Copyright © 2015 The Authors Terms and Conditions


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