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A Novel and Reliable Method to Detect Microsatellite Instability in Colorectal Cancer by Next-Generation Sequencing  Lizhen Zhu, Yanqin Huang, Xuefeng.

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Presentation on theme: "A Novel and Reliable Method to Detect Microsatellite Instability in Colorectal Cancer by Next-Generation Sequencing  Lizhen Zhu, Yanqin Huang, Xuefeng."— Presentation transcript:

1 A Novel and Reliable Method to Detect Microsatellite Instability in Colorectal Cancer by Next-Generation Sequencing  Lizhen Zhu, Yanqin Huang, Xuefeng Fang, Chenglin Liu, Wanglong Deng, Chenhan Zhong, Jinghong Xu, Dong Xu, Ying Yuan  The Journal of Molecular Diagnostics  Volume 20, Issue 2, Pages (March 2018) DOI: /j.jmoldx Copyright © 2018 American Society for Investigative Pathology and the Association for Molecular Pathology Terms and Conditions

2 Figure 1 The percentages of length-instability loci in MSS and MSI-H samples for the ColonCore panel, MSIsensor, and mSINGS. Each dot represents one sample. The percentages are more readily distinguished in the ColonCore panel versus those from MSIsensor and mSINGS. The Journal of Molecular Diagnostics  , DOI: ( /j.jmoldx ) Copyright © 2018 American Society for Investigative Pathology and the Association for Molecular Pathology Terms and Conditions

3 Figure 2 Mutation burden of MSS and MSI-H samples reported by the PCR method. Each dot represents one sample. The mutation burden is not highly distinguishable between these two types of samples. The Journal of Molecular Diagnostics  , DOI: ( /j.jmoldx ) Copyright © 2018 American Society for Investigative Pathology and the Association for Molecular Pathology Terms and Conditions

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