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Screening individuals with intracranial aneurysms for abdominal aortic aneurysms is cost-effective based on estimated coprevalence  Benjamin Z. Ball,

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Presentation on theme: "Screening individuals with intracranial aneurysms for abdominal aortic aneurysms is cost-effective based on estimated coprevalence  Benjamin Z. Ball,"— Presentation transcript:

1 Screening individuals with intracranial aneurysms for abdominal aortic aneurysms is cost-effective based on estimated coprevalence  Benjamin Z. Ball, MD, Boxiang Jiang, MD, Prachi Mehndiratta, MBBS, George J. Stukenborg, PhD, Gilbert R. Upchurch, MD, James F. Meschia, MD, Bradford B. Worrall, MD, MSc, Andrew M. Southerland, MD, MSc  Journal of Vascular Surgery  Volume 64, Issue 3, Pages e3 (September 2016) DOI: /j.jvs Copyright © 2016 Society for Vascular Surgery Terms and Conditions

2 Fig 1 Monte Carlo probabilities distribution of incremental cost-effectiveness ratio (ICER). A cohort of 10,000 patients harboring intracranial aneurysm (IA) was simulated to undergo ultrasound screening for abdominal aortic aneurysm (AAA). The probabilities distribution of the cost-effectiveness of the screening was plotted in this figure. The cost-effectiveness of the screening was represented by the ICER ($/QALY) as plotted on the x-axis. QALY, Quality-adjusted life-year. Journal of Vascular Surgery  , e3DOI: ( /j.jvs ) Copyright © 2016 Society for Vascular Surgery Terms and Conditions

3 Fig 2 Monte Carlo simulations of incremental cost per quality-adjusted life-year (QALY) gained by ultrasound screening for abdominal aortic aneurysm (AAA) on a cohort of 10,000 patients harboring intracranial aneurysm (IA). The dashed line indicates the threshold of willingness to pay of $60,000/QALY. Dots below the dashed line are situations in which ultrasound screening for AAA is cost-effective. Journal of Vascular Surgery  , e3DOI: ( /j.jvs ) Copyright © 2016 Society for Vascular Surgery Terms and Conditions

4 Supplementary Fig 1 (online only)
Decision tree (TreeAge Pro 2015, Williamstown, Mass) evaluating the cost-effectiveness of ultrasound screening for abdominal aortic aneurysm (AAA) in patients harboring intracranial aneurysm (IA). MI, Myocardial infarction; MLE, mean life expectancy. Journal of Vascular Surgery  , e3DOI: ( /j.jvs ) Copyright © 2016 Society for Vascular Surgery Terms and Conditions

5 Supplementary Fig 2 (online only)
Cost-effectiveness of ultrasound screening for abdominal aortic aneurysm (AAA) in patients harboring intracranial aneurysm (IA) as a function of the coprevalence of IA and AAA. The screening arm dominated the model when the coprevalence is above 3.7%. ICER, Incremental cost-effectiveness ratio; QALY, quality-adjusted life-year. Journal of Vascular Surgery  , e3DOI: ( /j.jvs ) Copyright © 2016 Society for Vascular Surgery Terms and Conditions

6 Supplementary Fig 3 (online only)
Cost-effectiveness of ultrasound screening for abdominal aortic aneurysm (AAA) in patients harboring intracranial aneurysm (IA) as a function of 5-year rupture rate of inoperable AAA (AAA size between 3 and 5.5 cm). The screening arm dominated the model when the 5-year rupture rate of inoperable AAA is above 5.5%. ICER, Incremental cost-effectiveness ratio; QALY, quality-adjusted life-year. Journal of Vascular Surgery  , e3DOI: ( /j.jvs ) Copyright © 2016 Society for Vascular Surgery Terms and Conditions

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