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A Model to Predict the Use of Surgical Resection for Advanced-Stage Non-Small Cell Lung Cancer Patients  Elizabeth A. David, MD, Stina W. Andersen, PhD,

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Presentation on theme: "A Model to Predict the Use of Surgical Resection for Advanced-Stage Non-Small Cell Lung Cancer Patients  Elizabeth A. David, MD, Stina W. Andersen, PhD,"— Presentation transcript:

1 A Model to Predict the Use of Surgical Resection for Advanced-Stage Non-Small Cell Lung Cancer Patients  Elizabeth A. David, MD, Stina W. Andersen, PhD, Laurel A. Beckett, PhD, Joy Melnikow, MD, MPH, Karen Kelly, MD, David T. Cooke, MD, Lisa M. Brown, MD, MAS, Robert J. Canter, MD, MAS  The Annals of Thoracic Surgery  Volume 104, Issue 5, Pages (November 2017) DOI: /j.athoracsur Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Cohort of stage IIIA, IIIB, and IV patients from the National Cancer Database (NCDB) Participant Use Files (PUF). (NSCLC = non-small cell lung cancer; TNM = tumor-node-metastasis.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 Logistic regression models used to develop the Surgical Selection Score. *Represents variables without significant predictive ability for selection for surgical intervention. The final model was model 6. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

4 Fig 3 Distribution of treatment regimens in (A) nonsurgically and (B) surgically treated advanced-stage non-small cell lung cancer patients. The nonsurgical cohort is 94% of the total and the surgical cohort is 6%. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

5 Fig 4 Distribution of Surgical Selection Score and probability of undergoing surgical intervention for the (A) entire cohort and by (B) stage IIIA, (C), stage IIIB, and (D) stage IV. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

6 Fig 5 Kaplan-Meier survival analysis of patients stratified by treatment group by (A) the lowest, (B) second, (C) third, and (D) fourth Surgical Selection Score quartile. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

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