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Paul Manka, Lars P. Bechmann, Jason D

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1 Hepatitis E Virus Infection as a Possible Cause of Acute Liver Failure in Europe 
Paul Manka, Lars P. Bechmann, Jason D. Coombes, Viktoria Thodou, Martin Schlattjan, Alisan Kahraman, Wing-Kin Syn, Fuat Saner, Guido Gerken, Hideo Baba, Jens Verheyen, Jörg Timm, Ali Canbay  Clinical Gastroenterology and Hepatology  Volume 13, Issue 10, Pages e2 (October 2015) DOI: /j.cgh Copyright © 2015 AGA Institute Terms and Conditions

2 Figure 1 Results of HEV serology and HEV RNA testing of the 80 detected patients with ALF and differentiation between negative, indeterminate, and positive results. Twelve patients tested positive for anti-HEV IgG, of whom 2 were indeterminate and 2 were positive for anti-HEV IgM. The 2 patients with positive anti-HEV IgM also were positive for HEV RNA. One patient had indeterminate testing for anti-HEV IgG but tested negative for anti-HEV IgM as well as for HEV RNA. Three of the patients who tested negative for anti-HEV IgG showed positive results for anti-HEV IgM and consequently for HEV RNA. One patient who tested negative for anti-HEV IgG and IgM showed a positive result for HEV RNA. PCR, polymerase chain reaction. Clinical Gastroenterology and Hepatology  , e2DOI: ( /j.cgh ) Copyright © 2015 AGA Institute Terms and Conditions


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