1. GROUP 6 : INTRAOCULAR LENS IMPLANT
Amir Mustakim Ab Rashid
Nurdania Abd Rahman
Nur Nadhirah Abdul Hamid
Keerthana a/p Rangasamy

2. HISTORY IN DEVELOPMENT
PRESENTATION OUTLINE 1
REGION OF INTEREST 2
CLINICAL NEEDS 3
HISTORY IN DEVELOPMENT 4
IOL MODEL

3. STRUCTURE OF THE EYE

4. LENS
Lens flattened,
Distant vision
Lens bulged,
Near vision

5. Intraocular Lens (IOL)
Cataracts
Intraocular Lens (IOL)

6. Clinical Needs What is Intraocular Lens Implant?
Synthetic and artificial lens implanted inside eyes to
replace natural lens during cataracts surgery
Also are used for a type of vision correction surgery
called refractive lens exchange
The best intraocular lens depends on many factors,
including lifestyle and patients specific visual needs.
Why IOL is needed?
When natural lens is removed, much of the eye's focusing ability is lost. To restore vision, IOL is needed to replaced the focusing power that lost.

7. Cataract Surgery Technique
Phacoemulsification Technique
Extracapsular Technique

8. Phacoemulsification technique (small incision)
A. An incision is first made in the
cornea, the outer covering of the eye
B. A phacoemulsification instrument
uses ultrasonic waves to break up the
cataract
C. Pieces of the cataract are then
suctioned out
D. To repair the patient's vision, a
folded intraocular lens is pushed
through the same incision
E. opened in place 

9. Phacoemulsification instrument

10. Extracapsular technique
An incision is made in the eye just
beneath the iris, or colored part
B. The diseased lens is pulled out
C. A prosthetic intraocular lens is
place through the incision
D. Opened to replace the old lens

12. Cont… Minimum age allowed for IOL implant
The use of an IOL in the first year of life, especially in the first few
months of life, is investigational.
IOL is a viable option for infants. However, there was an
increased risk of complications and need for additional surgeries.
If a contact lens or glasses are used initially, secondary IOL
insertion can be considered when the child is older and eye growth more complete.
Use of an intraocular lens is an individualized decision for each
child made after discussion with the ophthalmologist.

13. Cont… Lens Design And Manufacturer
Plastic material most frequently used - polymethylmethacrylate (PMMA)
Considerations for lens design and manufacturer:
lens materials used for the optic and haptic (loop) portions of
the device.
techniques of lens manufacture
Quality Control
Evaluation of the lenses by surgeon

14. Cont…
Differences between standard cataract surgery and Laser Cataract surgery

15. HISTORY IN DEVELOPMENT OF IOLs
Generation V
PC IOLs
Generation III
Iris-supported IOLs
Generation I
Ridley IOLs
1992-
present
Generation II
Early AC-IOLs
Generation IV
AC IOLs
Generation VI
Modern Capsular
surgery

16. GENERATION I - Ridley IOL
Dr Ridley
Biconvex polymethylmethacrylate (PMMA) disk
Implanted after extracapsular cataract extraction (ECCE)
Problems with decentration and dislocations

17. GENERATION II - Early AC IOLs
Dr Baron
New implantation site—the anterior chamber, with fixation of the lens in the angle recess.
Little chance of dislocation with implantation in the narrow confines of
the anterior chamber
High rate of corneal decompensation (corneal endothelium fail to maitain dehydrate)

18. GENERATION III - Iris-supported IOLs
Dr Binkhorst
Introduced four-loop iris-clip IOL
Decreased the amount of chafing against uveal tissues and decreased the incidence of complications such as inflammation

19. GENERATION IV - AC IOLs Dr Choyce
The rigid Choyce-style lenses produced
By the mid to late 1970s, several other manufacturers in the U.S.
produced defective copies of the Choyce design, illustrated in the
scanning electron micrograph- (ocular tissue damage)
Modern Choyce IOL and various three- and four-point fixation,
open-loop, one piece all-PMMA designs with no positioning holes in
the fixation haptics

20. Cont... Scanning electron micrograph of a poorly manufactured copy
of a Choyce rigid IOL.
Modern four-point fixation open-loop AC-IOL
design
Modern three-point-fixation
open-loop one-piece all-PMMA
AC-IOL
well-manufactured Choycestyle
IOL.

21. GENERATION V - ECCE PC IOLs
Dr John Pearce
Rigid tripod design (two inferior feet -
implanted in the capsular bag, the superior
foot - implanted in front of the anterior
capsule, sutured to the iris)
Dr. Steven Shearing
PC-IOL consisting of an optic with two
flexible J-shaped loops

22. Cont.. Dr William Simcoe Long C-looped posterior chamber lens
Dr. Robert Sinskey
Introduced various modified J-loop designs

23. GENERATION VI - Modern capsular surgery
Implantation of IOLs through can-opener capsulotomies
The newly developed “capsular lenses” fabricated from both rigid and
soft materials

24. Medical Device Manufacturer

25. 1. OCULENTIS Intraocular Lenses
IOL manufacturer Oculentis based in Berlin and its
production facilities in Netherlands
It has its own research and development department
Currently working to expand the development of
toric multifocal and accommodative IOL .

26. LENTIS Mplus Xtoric LU-313 MF30T
Multifocal with sectorshaped near vision segment
Biconvex, Aspherical and toric surface-posterior, sector shaped nearvision segment anterior

27. 2. Hoya Surgical Optics
Began in 1987 when a team of researches led by Kosugi-san
brought the first HOYS IOL to market in Japan
One of the largest global IOL companies

28. Vivinex XY1
Hydrophobic acrylic pseudophakic IOL, with aspheric monofocal optic design and blue light filter
iSert 150
Pseudophakic acrylic hydrophobic preloaded IOL with spheric monofocal optic

29. 3. ZEISS Intraocular Lenses
The Carl Zeiss group is an international leader in the fields of optics and opto-electronics.
In addition to IOLs, also manufactures planetariums, spectacle lenses, photographic and cinema cameras, as well as solutions for biomedical research and the semiconductor, automotive and engineering industries in general

30. CT ASPHINA 409MP preloaded AT LISA tri 839MP
Aspheric Multifocal Trifocal
Preloaded, monofocal aspheric

31. 4. STAAR SURGICAL
Design, developed, manufactured and sold intraocular lenses and systems associated to their implant for over 25 years
All of its lenses are foldable which enables surgeons to insert them through micro incisions

32. Lente Visian ICL
The phakic lens material Vision ICL is Collamer (Collagen and Polymer), a material exclusively developed by STAAR
Collagen, offers an optimum level of biocompatibility and can provide exceptional optical quality

33. 5. Physiol Intraocular Lenses
Founded in 1986
Specialised in the research, development and manufacture of IOL for cataract

34. FINEVISION (MICRO F)
The Finevision IOL optic combines two diffractive structures which are adjusted to offer additions of dioptres (for near vision) and dioptres ( for intermediate vision) respectivel

35. 6. Bausch+Lomb Intraocular Lenses
Began operating in 1853 in Rochester (USA)
It began to establish in 20th century, when it produced the first high quality optical lens in America, developed solar lenses for use in the First World War and created the used for taking the first satellite photographs of the moon
By 1971, it was a pioneer in the introduction of soft contact lenses and today it is largest supplier of eye care products in the world

36. enVista TORIC MX60T
Akreos AO-60
Aspheric Monofocal
Aspheric Monofocal

37. 7. AMO (Abbott Medical Optics) Intraocular Lenses
Founded in 1880 and based in the USA
AMO has established itself as the world’s number one company in LASIK, second in the treatment of cataracts and IOL and third in eye solutions

38. TECNIS Multifocal
1-Piece Aspheric Multifocal Hydrophobic Acrylic IOL

39. Types of Intraocular Lenses (IOL)
Monofocal Lens
Mutifocal Lens
Toric Lens
Accommodative Lens

40. Types of Intraocular Lenses (IOL)
Monofocal Lens
Only have one focusing distance either
near, far,
intermediate
depending on needs
Multifocal Lens
Have more than one focusing distance
Toric Lens
For treat cataracts as well as to reduce
astigmatism
Accommodative Lens
Able to move and focus various distance

42. Thank you