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A Randomized, Multicenter, Open-Label Trial to Determine Peritonitis Rate, Product Defect, and Technique Survival Between ANDY-Disc® and UltraBag® in.

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Presentation on theme: "A Randomized, Multicenter, Open-Label Trial to Determine Peritonitis Rate, Product Defect, and Technique Survival Between ANDY-Disc® and UltraBag® in."— Presentation transcript:

1 A Randomized, Multicenter, Open-Label Trial to Determine Peritonitis Rate, Product Defect, and Technique Survival Between ANDY-Disc® and UltraBag® in Patients on CAPD  Hin-Seng Wong, MD, FRCP(E), Loke-Meng Ong, MRCP(UK), Teck-Onn Lim, FRCP(E), Lai-Seong Hooi, FRCP(E), Zaki Morad, FRCP(E), Rozina Ghazalli, FRCP(E), Wan Shaariah, FRCP(E), Yam-Ngo Lim, FRCP(E), Ghazali Ahmad, MMed, Bak-Leong Goh, FRCP(Glasgow), Lynster Liaw, MRCP(UK), Susan Pee, MRCP(UK), Ming-Lee Lee, MRCP(UK)  American Journal of Kidney Diseases  Volume 48, Issue 3, Pages (September 2006) DOI: /j.ajkd Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

2 Fig 1 The Fresenius ANDY-Disc system uses the control disc to direct dialysate flow. The Y-tubing connection is built in to the control disc that consists of a PIN system; turning the knob in the control disc from position 1 to 4 will complete the CAPD exchange cycle. American Journal of Kidney Diseases  , DOI: ( /j.ajkd ) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

3 Fig 2 The Baxter UltraBag system uses clamps situated before the Y connection to direct dialysate flow. The CAPD exchange cycle consists of draining the effluent (white clamp open, blue clamp closed), flush before fill (both clamps open), and filling fresh dialysate into the peritoneal cavity (white clamp closed, blue clamp open). American Journal of Kidney Diseases  , DOI: ( /j.ajkd ) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

4 Fig 3 Trial profile. American Journal of Kidney Diseases  , DOI: ( /j.ajkd ) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

5 Fig 4 Treatment effect (IRR) by center and pooled estimate (per-protocol analysis). American Journal of Kidney Diseases  , DOI: ( /j.ajkd ) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

6 Fig 5 Relationship between product defect and peritonitis for ANDY-Disc. (○), Peritonitis count; (Δ), product defect. American Journal of Kidney Diseases  , DOI: ( /j.ajkd ) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

7 Fig 6 Relationship between product defect and peritonitis for UltraBag. (○), Peritonitis; (Δ), product defect. American Journal of Kidney Diseases  , DOI: ( /j.ajkd ) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

8 Fig 7 CAPD technique survival (0 to 12 months) by treatment arms (P > 0.05). American Journal of Kidney Diseases  , DOI: ( /j.ajkd ) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions


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