1. 28 October 2011 Begin Ch 12 Cardiovascular Physiology
6 sections p
2 CV labs: 1 Frog heart, 1 Human EKG and Blood Pressure
Abstracts due Monday at start of class.

2. 1QQ # 22 for 8:30
Write a question based on Control of Movement chapter and lecture material.
Provide an answer to your question.
Questions that require insight and integration earn more points than questions requiring only recall of information.

3. 1QQ # 22 for 9:30
Write a question based on Control of Movement chapter and lecture material.
Provide an answer to your question.
Questions that require insight and integration earn more points than questions requiring only recall of information.

4. S
S 1
Secretion
Reabsorption
Filtration

5. Circulatory System Circulates
Nutrients: glucose, amino acids, fatty acids, ketones, etc
Wastes:
Hormones: bound & free
Gases: CO2 and O2
Formed Elements: Cells and Cell Fragments
Erythrocytes, Leukocytes, Thrombocytes = Platelets
Other roles of the Cardiovascular System
Thermoregulation
Blood Clotting
Reproduction (ex: penile erection)

6. Entering and Exiting the blood
S 3
Blood volume ~ 5 liters
Figure 12.01
Serum = plasma – clotting factors
Entering and Exiting the blood
Components……
EPO and “The Scoop on Tissie”
Discontinuous capillaries in bone marrow, spleen, & liver permit erythrocytes to enter and exit blood.
Formed elements
Hct = percentage of blood volume occupied by RBCs
Anemia
Blood doping & erythropoietin (hormone that stimulates erythrocyte production in bone marrow) to increase hematocrit

7. Arteries..away from heart Veins..return to heart
Fig
When left heart can’t pump all the blood it receives from pulmonary circuit (due to high aortic pressure and/or damage to left ventricle) blood accumulates in pulmonary circuit. This is congestive heart failure. Symptom: shortness of breath.
S 4
Arteries..away from heart Veins..return to heart
Regional blood flow determined by arteries and arterioles.
12.02.jpg
Resting Cardiac Output = 5L/min for each side!

8. CO = 5L/min for each circuit
Figure 12.04
S 5
CO = 5L/min for each circuit
Up to 35 L/min in strenuous exercise

9. What’s missing? Microcirculation Exchange Vessels S 6
Pulmonary circuit
CO = 5 liters/min
CO = 5 liters/min
Arterial Blood Pressure
Recall Portal Systems!
Systemic Circuit
Resistance Vessels
Microcirculation
Exchange Vessels
Capacitance vessels

10. S 7
Pulmonary circuit
Pressure gradients makes fluids move.
Moving fluids flow, but flow is limited by resistance. Resistance creates pressure.
Systemic Circuit

11. Q= ΔP πr4 8Lη Poiseulle’s equation
F=Q=ΔP/R
Flow = Pressure gradient/Resistance
from Ohm’s Law (V=IR)
Radius of arterioles regulates Q to organs
Double radius … 16x flow
Half radius….1/16th flow
R = 8Lη/πr4
Q= ΔP πr4 8Lη Poiseulle’s equation
Smooth muscles determine radius

12. Cardiac Output = Heart Rate X Stroke Volume CO = HR x SV 5L/min = 72 beat/min x 70 ml/beat
The Cardiac Cycle animation