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Allogeneic Hematopoietic Stem Cell Transplantation for Adolescents and Young Adults with Acute Myeloid Leukemia  Daisuke Tomizawa, Shiro Tanaka, Tadakazu.

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Presentation on theme: "Allogeneic Hematopoietic Stem Cell Transplantation for Adolescents and Young Adults with Acute Myeloid Leukemia  Daisuke Tomizawa, Shiro Tanaka, Tadakazu."— Presentation transcript:

1 Allogeneic Hematopoietic Stem Cell Transplantation for Adolescents and Young Adults with Acute Myeloid Leukemia  Daisuke Tomizawa, Shiro Tanaka, Tadakazu Kondo, Yoshiko Hashii, Yasuyuki Arai, Kazuko Kudo, Takashi Taga, Takahiro Fukuda, Hiroaki Goto, Jiro Inagaki, Katsuyoshi Koh, Kazuteru Ohashi, Yukiyasu Ozawa, Masami Inoue, Koji Kato, Junji Tanaka, Yoshiko Atsuta, Souichi Adachi, Hiroyuki Ishida  Biology of Blood and Marrow Transplantation  Volume 23, Issue 9, Pages (September 2017) DOI: /j.bbmt Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

2 Figure 1 Comparison of outcomes between adolescent and young adult (15 to 29 years old) and child (0 to 14 years old) patients with AML after hematopoietic stem cell transplantation in the total cohort (all transplant recipients from 1990 to 2013). (A) Shows overall survival, (B) shows disease-free survival; (C) shows cumulative incidence of relapse; and (D) shows treatment-related mortality. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

3 Figure 2 Cause of treatment-related death among (A) adolescent and young adult (15 to 29 years old) patients and (B) child (0 to 14 years old) patients. aGVHD indicates acute graft-versus-host disease; ARDS,  acute respiratory distress syndrome; cGVHD,  chronic graft-versus-host disease; IP,  interstitial pneumonia; SOS,  sinusoidal obstruction syndrome; TMA, thrombotic microangiopathy; VOD  veno-occlusive disease. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

4 Figure 3 Comparison of outcomes between adolescent and young adult (15 to 29 years old) and child (0 to 14 years old) patients with AML after hematopoietic stem cell transplantation in the recent cohort (recipients of transplants with high-resolution HLA typing from 2000 to 2013). (A) Shows overall survival, (B) shows disease-free survival, (C) shows cumulative incidence of relapse, and (D) shows treatment-related mortality. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions


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