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US and European Perspectives on Sinusoidal Obstruction Syndrome

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Presentation on theme: "US and European Perspectives on Sinusoidal Obstruction Syndrome"— Presentation transcript:

1 US and European Perspectives on Sinusoidal Obstruction Syndrome

2

3 Overview

4 Overview (cont)

5 Overview (cont)

6 Risk Assessment: CIBMTR VOD Risk Model

7 CIBMTR VOD Risk Model

8 Age and Risk of VOD/SOS

9 Conditioning Regimen and Risk of VOD/SOS

10 Observed VOD/SOS Among 4 Risk Groups

11 Preventing SOS

12 New EBMT Criteria for Diagnosing SOS/VOD in Adults

13 New EBMT Criteria for Diagnosing SOS/VOD in Adults (cont)

14 New EBMT Criteria for Severity Grading of Suspected SOS/VOD in Adults

15 EBMT Guidelines for Managing SOS/VOD

16 EBMT Guidelines for Managing SOS/VOD (cont)

17 Adverse Events Associated With Defibrotide in the International Compassionate Use Program

18 Other Measures for Treating SOS/VOD

19 Other Measures for Treating SOS/VOD (cont)

20 Summary

21 Abbreviations

22 Abbreviations (cont)


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