1. Horizontal gene transfer
Maddalen Arizti Lopez de Aberasturi
Genomics

2. Index Horizontal gene transfer Mechanisms Detection methods
Importance of HGT
Conclusion

3. Horizontal gene transfer (HGT)
Transfer of genes between organisms in a manner other than traditional reproduction
Acquisition of foreign genes  evolution of many organisms
Organism
Prokaryotes
Eukaryotes

5. Mechanisms of HGT

6. Mechanisms of HGT

7. Detection methods Phylogenetic methods Phylogeny independent methods
Codon-based approaches
BLAST
PCR-based approaches

8. Importance of HGT Adaptative advantages Bdelloid Rotifer
Functional bacteria, plants and fungal genes
Biochemistry improvements
Evolution of eukaryotes
Plantae  plastids
Red algae  5% of coding genes
Glaucophytes  400 genes
Green plant
Implications for medicine and biotechnology
Important role in pathogenesis
Therapeutic targets
Antibiotic resistance  vaccines

9. Conclusion Study of mechanism in eukaryotes
Evolutionary potential in all the organism
More frequent in eukaryotes than we though
Importance for medicine and new therapies

10. Thank you for listening! Questions