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Cryptococcus neoformans var

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Presentation on theme: "Cryptococcus neoformans var"— Presentation transcript:

1 Cryptococcus neoformans var
Cryptococcus neoformans var. neoformans resistant to fluconazole in an HIV-negative patient with chronic lymphocytic leukemia  K. Assing, H. Birgens, M. Arendrup  Clinical Microbiology and Infection  Volume 9, Issue 5, Pages (May 2003) DOI: /j x Copyright © 2003 European Society of Clinical Infectious Diseases Terms and Conditions

2 FIG. 1 Etest susceptibility testing of fluconazole and amphotericin B. Susceptibility testing was performed according to the manufacturer's recommendations. The isolate was regarded as fluconazole resistant. The Etest endpoint of amphotericin B was 0.25 mg/L. Clinical Microbiology and Infection 2003 9, DOI: ( /j x) Copyright © 2003 European Society of Clinical Infectious Diseases Terms and Conditions

3 FIG. 2 Seventy-two-hour reading of NCCLS microdilution susceptibility determination. Growth inhibition curve with two-fold drug dilutions and untreated control cultures. OD values read by spectrophotometer. Fluconazole 80% inhibition cut-off 0.122, amphotericin B cut-off MICs: fluconazole 32 mg/L, amphotericin B 1 mg/L. Ampho, amphotericin B; Fluco, fluconazole. Clinical Microbiology and Infection 2003 9, DOI: ( /j x) Copyright © 2003 European Society of Clinical Infectious Diseases Terms and Conditions


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