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Assessing Atrial Fibrillation: Real-World Data vs Clinical Trials

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Presentation on theme: "Assessing Atrial Fibrillation: Real-World Data vs Clinical Trials"— Presentation transcript:

1 Assessing Atrial Fibrillation: Real-World Data vs Clinical Trials

2

3 Program Goals

4 NOAC Trials Safety

5 NOAC Trials Mortality

6 From Trials to Clinical Practice

7 Real-World Data Administrative Databases

8 Registry Data

9 Medicare Database Dabigatran vs Warfarin

10 Underuse of OACs in Patients With AF

11 Why Were OACs Not Prescribed?

12 ORBIT-AF Lack of Patient Engagement

13 Warfarin TTR Is Not Ideal

14 ORBIT-AF TTR Is Not Ideal

15 ORBIT-AF Stable INR Is Not a Predictor of Future Control

16 NOAC Dosing

17 NOAC Underdosing

18 ORBIT-AF NOAC Dosing Outcomes

19 Adherence to NOAC Therapy

20 Temporary Interruptions in OAC

21 ORBIT-AF Temporary Interruptions in OAC

22 Bridging

23 Summary

24 Abbreviations


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