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Approach to the Treatment of Methanol Intoxication
Jeffrey A. Kraut, MD American Journal of Kidney Diseases Volume 68, Issue 1, Pages (July 2016) DOI: /j.ajkd Copyright © Terms and Conditions
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Figure 1 Metabolism of methanol. Methanol undergoes serial oxidation: methanol is catalyzed by the enzyme alcohol dehydrogenase to formaldehyde and then formaldehyde is catalyzed by the enzyme formaldehyde dehydrogenase to formic acid. Folinic acid given to a patient will accelerate the conversion to carbon dioxide (CO2) and water (H2O). Adapted from Rastogi et al11 with permission of the National Kidney Foundation. American Journal of Kidney Diseases , DOI: ( /j.ajkd ) Copyright © Terms and Conditions
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