1. Volume 84, Issue 3, Pages 425-426 (September 2013)
Journal Club 
Kidney International 
Volume 84, Issue 3, Pages (September 2013)
DOI: /ki
Copyright © 2013 International Society of Nephrology Terms and Conditions

2. Figure
αSMA+ myofibroblasts derive from resident tissue cells and bone marrow and functionally contribute to renal fibrosis. Immunolabeling for the total αSMA+ population (αSMA-FITC+, green) in the fibrotic kidneys of wild-type (WT) mice with bone marrow (BM) transplanted from an αSMA–red fluorescent protein donor (n = 5). The graph on the right shows the numbers of total αSMA+ cells (αSMA-FITC+, green) and αSMA+ cells from the bone marrow (αSMA-RFP+αSMA-FITC+; the relative percentage is shown).
Kidney International  , DOI: ( /ki )
Copyright © 2013 International Society of Nephrology Terms and Conditions

3. Figure
Schematic of CLARITY. Tissue is cross-linked with formaldehyde (red) in the presence of hydrogel monomers (blue), covalently linking tissue elements to monomers that are then polymerized into a hydrogel mesh (followed by a day-4 wash step). Electric fields applied across the sample in ionic detergent actively transport micelles into, and lipids out of, the tissue, leaving fine-structure and cross-linked biomolecules in place. The electrophoresis chamber is depicted in the boxed region.
Kidney International  , DOI: ( /ki )
Copyright © 2013 International Society of Nephrology Terms and Conditions