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AZD2563, a novel oxazolidinone: definition of antibacterial spectrum, assessment of bactericidal potential and the impact of miscellaneous factors on.

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Presentation on theme: "AZD2563, a novel oxazolidinone: definition of antibacterial spectrum, assessment of bactericidal potential and the impact of miscellaneous factors on."— Presentation transcript:

1 AZD2563, a novel oxazolidinone: definition of antibacterial spectrum, assessment of bactericidal potential and the impact of miscellaneous factors on activity in vitro  A. Wookey, P.J. Turner, J.M. Greenhalgh, M. Eastwood, J. Clarke, C. Sefton  Clinical Microbiology and Infection  Volume 10, Issue 3, Pages (March 2004) DOI: /j X x Copyright © 2004 European Society of Clinical Infectious Diseases Terms and Conditions

2 Fig. 1 Structure of AZD2563. Clinical Microbiology and Infection  , DOI: ( /j X x) Copyright © 2004 European Society of Clinical Infectious Diseases Terms and Conditions

3 Fig. 2 Cumulative percentage susceptibilities for AZD2563 and linezolid against recent clinical isolates (MR, Methicillin-resistant; MS, Methicillin-susceptible). Clinical Microbiology and Infection  , DOI: ( /j X x) Copyright © 2004 European Society of Clinical Infectious Diseases Terms and Conditions

4 Fig. 3 Time-kill assay for recent clinical isolates tested with AZD2563, linezolid and vancomycin at four times their respective MICs (MR, Methicillin-resistant). Clinical Microbiology and Infection  , DOI: ( /j X x) Copyright © 2004 European Society of Clinical Infectious Diseases Terms and Conditions


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