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Molecular Chaperones: Resurrection or destruction?

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Presentation on theme: "Molecular Chaperones: Resurrection or destruction?"— Presentation transcript:

1 Molecular Chaperones: Resurrection or destruction?
Arthur L. Horwich  Current Biology  Volume 5, Issue 5, Pages (May 1995) DOI: /S (95)

2 Figure 1 Pathways of ClpA/X action. In vitro, in the absence of ClpP, ATP-mediated dissociation of multimers is observed; in the presence of ClpP, ATP-mediated degradation is observed. Studies of E. coli mutants support a role of ClpA/P and ClpX/P in protein degradation in vivo; as yet a role in protein disaggregation or refolding remains to be observed for ClpA or ClpX in vivo. Current Biology 1995 5, DOI: ( /S (95) )


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