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Assembling Cell Ensembles

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Presentation on theme: "Assembling Cell Ensembles"— Presentation transcript:

1 Assembling Cell Ensembles
Nelson Spruston  Cell  Volume 157, Issue 7, Pages (June 2014) DOI: /j.cell Copyright © 2014 Elsevier Inc. Terms and Conditions

2 Figure 1 Schematic Depiction of Neuronal Development in the Hippocampus (A–C) Neuroepithelial cells near in the ventricular zone give rise to radial glial cells (RGCs) with a long process extending up to the hippocampal fissure. RGCs in turn divide to produce postmitotic neurons or intermediate progenitors (IPs) that later become neurons. Each color depicts a clonal cell line originating from an RGC labeled at embryonic day 12 (E12). (A) At E13-14, RGCs are oriented vertically. (B) By E16, RGC processes begin to bend, IPs begin to differentiate into neurons, and RGCs divide further, giving rise to astrocytes. (C) At E18 and later, RGC bending is more pronounced and neurons and astrocytes begin to take a more mature form and separate from the RGC. Cell  , DOI: ( /j.cell ) Copyright © 2014 Elsevier Inc. Terms and Conditions

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