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Synthetic Biology: Modulating the MAP Kinase Module

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1 Synthetic Biology: Modulating the MAP Kinase Module
Lee Bardwell  Current Biology  Volume 21, Issue 7, Pages R249-R251 (April 2011) DOI: /j.cub Copyright © 2011 Elsevier Ltd Terms and Conditions

2 Figure 1 The MAP kinase module.
Top: The MAP kinase cascade module that O'Shaughnessy et al. [1] transplanted into yeast, emphasizing the cascaded dual phosphorylation mechanism. Bottom: An example of an input–output (dose–response) curve, where the input is active Raf and the output is the percentage of dually-phosphorylated (hence active) MAPK. Current Biology  , R249-R251DOI: ( /j.cub ) Copyright © 2011 Elsevier Ltd Terms and Conditions


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