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Risk stratification after paracetamol overdose using mechanistic biomarkers: results from two prospective cohort studies  James W Dear, FRCP, Joanna I.

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Presentation on theme: "Risk stratification after paracetamol overdose using mechanistic biomarkers: results from two prospective cohort studies  James W Dear, FRCP, Joanna I."— Presentation transcript:

1 Risk stratification after paracetamol overdose using mechanistic biomarkers: results from two prospective cohort studies  James W Dear, FRCP, Joanna I Clarke, BSc, Ben Francis, PhD, Lowri Allen, MBChB, Jonathan Wraight, MD, Jasmine Shen, MBChB, Prof Paul I Dargan, FRCP, David Wood, MD, Jamie Cooper, MD, Prof Simon H L Thomas, MD, Andrea L Jorgensen, PhD, Prof Munir Pirmohamed, FRCP, Prof B Kevin Park, PhD, Daniel J Antoine, PhD  The Lancet Gastroenterology & Hepatology  Volume 3, Issue 2, Pages (February 2018) DOI: /S (17) Copyright © 2018 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND 4.0 license Terms and Conditions

2 Figure Study profile Summary of the patient outcome pathways for all patients prospectively recruited to the (A) derivation (MAPP) and (B) validation (BIOPAR) cohorts. ALT=alanine aminotransferase. INR=international normalised ratio. The Lancet Gastroenterology & Hepatology 2018 3, DOI: ( /S (17) ) Copyright © 2018 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND 4.0 license Terms and Conditions


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