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Development and Validation Of a Highly Sensitive and Specific Gene Expression Classifier To Prospectively Screen and Identify B-Precursor Acute Lymphoblastic.

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Presentation on theme: "Development and Validation Of a Highly Sensitive and Specific Gene Expression Classifier To Prospectively Screen and Identify B-Precursor Acute Lymphoblastic."— Presentation transcript:

1 Development and Validation Of a Highly Sensitive and Specific Gene Expression Classifier To Prospectively Screen and Identify B-Precursor Acute Lymphoblastic Leukemia (ALL) Patients With a Philadelphia Chromosome-Like (“Ph-like” or “BCR-ABL1-Like”) Signature For Therapeutic Targeting and Clinical Intervention by Richard C. Harvey, Huining Kang, Kathryn G. Roberts, I-Ming L. Chen, Susan R. Atlas, Edward J. Bedrick, Julie M. Gastier-Foster, Jinghui Zhang, Daniela S. Gerhard, Malcolm A. Smith, Eric C. Larsen, Elizabeth A. Raetz, Naomi J. Winick, William L. Carroll, Eileen Stonerock, Nyla A. Heerema, Andrew J. Carroll, Shann-Ching Chen, Guangchun Song, Jared Becksfort, Michael Rusch, Yongjin Li, Jing Ma, Denise Ell, Shalini C. Reshmi, Mignon L. Loh, Meenakshi Davidas, Stephen P. Hunger, Charles G. Mullighan, and Cheryl L. Willman Blood Volume 122(21): November 15, 2013 ©2013 by American Society of Hematology

2 Huining Kang et al. Blood 2013;122:826
©2013 by American Society of Hematology

3 Survival Curves of 15-Gene Model: Performance in Test Set and Correlation with IKZF1 Deletions.
Huining Kang et al. Blood 2013;122:826 ©2013 by American Society of Hematology

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