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Radiation resistance and stem-like cells in brain tumors

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1 Radiation resistance and stem-like cells in brain tumors
Dolores Hambardzumyan, Massimo Squartro, Eric C. Holland  Cancer Cell  Volume 10, Issue 6, Pages (December 2006) DOI: /j.ccr Copyright © 2006 Elsevier Inc. Terms and Conditions

2 Figure 1 Stem-like cells in brain tumors
Immunofluorescence images of fresh-frozen sections of a human medulloblastoma showing localized regions of cells expressing the stem cell markers nestin (green) and Notch receptor (red) that work well in histochemical staining. Nuclei are stained blue with DAPI. Note that these stem-like cells are located in a specific region, or niche, rather than distributed randomly throughout the tumor. Scale bar, 20 μm. Cancer Cell  , DOI: ( /j.ccr ) Copyright © 2006 Elsevier Inc. Terms and Conditions


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