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2 copyright cmassengale
Mitosis Quiz copyright cmassengale

3 Name the Stages of Mitosis:
Early prophase Early Anaphase Metaphase Interphase Early Telophase, Begin cytokinesis Late Prophase Late telophase, Advanced cytokinesis Mid-Prophase Late Anaphase copyright cmassengale

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Identify the Stages ? Early, Middle, & Late Prophase ? ? ? Metaphase Anaphase Late Prophase ? ? ? Telophase & Cytokinesis Late Anaphase Telophase copyright cmassengale

5 Locate the Four Mitotic Stages in Plants
Anaphase Telophase Metaphase Prophase copyright cmassengale

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Uncontrolled Mitosis If mitosis is not controlled, unlimited cell division occurs causing cancerous tumors Oncogenes are special proteins that increase the chance that a normal cell develops into a tumor cell Cancer cells copyright cmassengale

7 Meiosis Formation of Gametes (Eggs & Sperm)
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Facts About Meiosis Preceded by interphase which includes chromosome replication Two meiotic divisions --- Meiosis I and Meiosis II Called Reduction- division Original cell is diploid (2n) Four daughter cells produced that are monoploid (1n) copyright cmassengale

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Facts About Meiosis Daughter cells contain half the number of chromosomes as the original cell Produces gametes (eggs & sperm) Occurs in the testes in males (Spermatogenesis) Occurs in the ovaries in females (Oogenesis) copyright cmassengale

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More Meiosis Facts Start with 46 double stranded chromosomes (2n) After 1 division - 23 double stranded chromosomes (n) After 2nd division - 23 single stranded chromosomes (n)   Occurs in our germ cells that produce gametes copyright cmassengale

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Why Do we Need Meiosis? It is the fundamental basis of sexual reproduction Two haploid (1n) gametes are brought together through fertilization to form a diploid (2n) zygote copyright cmassengale

13 Fertilization – “Putting it all together”
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14 Replication of Chromosomes
Replication is the process of duplicating a chromosome Occurs prior to division Replicated copies are called sister chromatids Held together at centromere Occurs in Interphase Replication is the process of duplicating chromosome. The new copy of a chromosome is formed by DNA synthesis during S-phase. The chromosome copies are called sister chromatids. Sister chromatids are held together at the centromere. copyright cmassengale

15 A Replicated Chromosome
Gene X Sister Chromatids (same genes, same alleles) Homologs (same genes, different alleles) Homologs separate in meiosis I and therefore different alleles separate. copyright cmassengale

16 Meiosis Forms Haploid Gametes
Meiosis must reduce the chromosome number by half Fertilization then restores the 2n number from mom from dad child too much! meiosis reduces genetic content The right number! copyright cmassengale

17 Meiosis: Two Part Cell Division
Sister chromatids separate Meiosis I Meiosis II Homologs separate Diploid Diploid Haploid copyright cmassengale

18 Meiosis I: Reduction Division
Nucleus Spindle fibers Nuclear envelope Early Prophase I (Chromosome number doubled) Late Prophase I Metaphase I Anaphase I Telophase I (diploid) copyright cmassengale

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Prophase I Late prophase Chromosomes condense. Spindle forms. Nuclear envelope fragments. Early prophase Homologs pair. Crossing over occurs. copyright cmassengale

20 Tetrads Form in Prophase I
Homologous chromosomes (each with sister chromatids)   Join to form a TETRAD Called Synapsis copyright cmassengale

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Crossing-Over Homologous chromosomes in a tetrad cross over each other Pieces of chromosomes or genes are exchanged Produces Genetic recombination in the offspring copyright cmassengale

22 Homologous Chromosomes During Crossing-Over
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Crossing-Over Crossing-over multiplies the already huge number of different gamete types produced by independent assortment copyright cmassengale

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Metaphase I Homologous pairs of chromosomes align along the equator of the cell copyright cmassengale

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Anaphase I Homologs separate and move to opposite poles. Sister chromatids remain attached at their centromeres. copyright cmassengale

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Telophase I Nuclear envelopes reassemble. Spindle disappears. Cytokinesis divides cell into two. copyright cmassengale

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Meiosis II Only one homolog of each chromosome is present in the cell. Gene X Meiosis II produces gametes with one copy of each chromosome and thus one copy of each gene. Sister chromatids carry identical genetic information. copyright cmassengale

28 Meiosis II: Reducing Chromosome Number
Prophase II Metaphase II Telophase II Anaphase II 4 Genetically Different haploid cells copyright cmassengale

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Prophase II Nuclear envelope fragments. Spindle forms. copyright cmassengale

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Metaphase II Chromosomes align along equator of cell. copyright cmassengale

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Anaphase II Equator Pole Sister chromatids separate and move to opposite poles. copyright cmassengale

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Telophase II Nuclear envelope assembles. Chromosomes decondense. Spindle disappears. Cytokinesis divides cell into two. copyright cmassengale

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Results of Meiosis Gametes (egg & sperm) form Four haploid cells with one copy of each chromosome One allele of each gene Different combinations of alleles for different genes along the chromosome copyright cmassengale

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Meiosis Animation copyright cmassengale

35 Oogenesis or Spermatogenesis
Gametogenesis Oogenesis or Spermatogenesis copyright cmassengale

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Spermatogenesis Occurs in the testes Two divisions produce 4 spermatids Spermatids mature into sperm Men produce about 250,000,000 sperm per day copyright cmassengale

37 Spermatogenesis in the Testes
Spermatid copyright cmassengale

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Spermatogenesis copyright cmassengale

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Oogenesis Occurs in the ovaries Two divisions produce 3 polar bodies that die and 1 egg Polar bodies die because of unequal division of cytoplasm Immature egg called oocyte Starting at puberty, one oocyte matures into an ovum (egg) every 28 days copyright cmassengale

40 Oogenesis in the Ovaries
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Oogenesis Oogonium (diploid) Mitosis Primary oocyte Meiosis I Secondary (haploid) Meiosis II (if fertilization occurs) First polar body may divide Polar bodies die Ovum (egg) Second polar body a A X Mature egg copyright cmassengale

42 Comparing Mitosis and Meiosis
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43 Comparison of Divisions
Mitosis Meiosis Number of divisions 1 2 Number of daughter cells 4 Genetically identical? Yes No Chromosome # Same as parent Half of parent Where Somatic cells Germ cells When Throughout life At sexual maturity Role Growth and repair Sexual reproduction copyright cmassengale


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