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Recurrent AA Amyloidosis in a Kidney Transplant

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Presentation on theme: "Recurrent AA Amyloidosis in a Kidney Transplant"— Presentation transcript:

1 Recurrent AA Amyloidosis in a Kidney Transplant
Sanjeev Sethi, MD, PhD, Mireille El Ters, MD, Srividya Vootukuru, MD, Qi Qian, MD  American Journal of Kidney Diseases  Volume 57, Issue 6, Pages (June 2011) DOI: /j.ajkd Copyright © 2011 National Kidney Foundation, Inc. Terms and Conditions

2 Figure 1 Time course of the patient's urine protein to osmolality ratio, serum creatinine (mg/dL), estimated glomerular filtration rate (eGFR; mL/min/1.73 m2), and serum albumin (S. Alb; g/dL) values after kidney transplant is shown. Arrows indicate the time of transplant biopsies. Conversion factor for units: serum creatinine concentration in mg/dL to μmol/L, ×88.4; eGFR in mL/min/1.73 m2 to mL/s/1.73 m2, × ; serum albumin in g/dL to g/L, ×10. American Journal of Kidney Diseases  , DOI: ( /j.ajkd ) Copyright © 2011 National Kidney Foundation, Inc. Terms and Conditions

3 Figure 2 (A) Periodic acid–Schiff–stained section shows mild or no mesangial expansion. (B) Congo Red stain shows positive staining along the artery and mild mesangial staining. (C) Positive serum amyloid A stain in an artery, interstitium, and glomerulus (A-C: original magnification, ×20). (D) Electron microscopy shows amyloid fibrils in a glomerulus (original magnification, ×46,000). American Journal of Kidney Diseases  , DOI: ( /j.ajkd ) Copyright © 2011 National Kidney Foundation, Inc. Terms and Conditions


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