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POPsicle for Fever! Cooling Down the Inflammasome

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Presentation on theme: "POPsicle for Fever! Cooling Down the Inflammasome"— Presentation transcript:

1 POPsicle for Fever! Cooling Down the Inflammasome
Kenichi Shimada, Timothy R. Crother, Moshe Arditi  Immunity  Volume 43, Issue 2, Pages (August 2015) DOI: /j.immuni Copyright © 2015 Elsevier Inc. Terms and Conditions

2 Figure 1 Mechanisms of Inflammasome Inhibition
Left: POP1 binds to the PYD of ASC and prevents PYD-PYD interactions between ASC and NLRP3. Right: multiple inflammasome inhibitory mechanisms are shown, including POP1. Immunity  , DOI: ( /j.immuni ) Copyright © 2015 Elsevier Inc. Terms and Conditions

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