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Effect of fibroids not distorting the endometrial cavity on the outcome of in vitro fertilization treatment: a retrospective cohort study  Lei Yan, M.D.,

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Presentation on theme: "Effect of fibroids not distorting the endometrial cavity on the outcome of in vitro fertilization treatment: a retrospective cohort study  Lei Yan, M.D.,"— Presentation transcript:

1 Effect of fibroids not distorting the endometrial cavity on the outcome of in vitro fertilization treatment: a retrospective cohort study  Lei Yan, M.D., Lingling Ding, M.D., Chunyan Li, M.D., Yu Wang, Ph.D., Rong Tang, M.D., Ph.D., Zi-Jiang Chen, M.D., Ph.D.  Fertility and Sterility  Volume 101, Issue 3, Pages e6 (March 2014) DOI: /j.fertnstert Copyright © 2014 American Society for Reproductive Medicine Terms and Conditions

2 Figure 1 Flow chart database searching pathway and group divisions.
Fertility and Sterility  , e6DOI: ( /j.fertnstert ) Copyright © 2014 American Society for Reproductive Medicine Terms and Conditions

3 Supplemental Figure 1 Schematic diagram of fibroids subclassification system. This figure shows the fibroid subclassification system that is adapted from Munro et al. (10). All patients with tumors inside the endometrial cavity or causing intracavitary distortion were termed submucosal (SM). Lesions not distorting the cavity but residing within the myometrium were labeled intramural (IM). Those extending predominantly outside the myometrium were termed subserosal (SS). SM includes type 0, 1, and 2. Fibroids that are attached to the endometrium by a narrow stalk are classified as type 0, whereas types 1 and 2 require a portion of the lesion to be IM—with type 1 being less than 50% and type 2 at least 50%. IM includes types 3, 4, and 5. Type 3 lesions are totally extracavitary but abut the endometrium. Type 4 lesions are entirely within the myometrium, with no extension to the endometrial surface or to the serosa. We include type 5, which is at least 50% IM, in the IM subgroup. SS includes types 6 and 7. Type 6 is less than 50% IM, and type 7 is attached to the serosa by a stalk. Fertility and Sterility  , e6DOI: ( /j.fertnstert ) Copyright © 2014 American Society for Reproductive Medicine Terms and Conditions

4 Supplemental Figure 2 ROC curve of SFD and TFD for patients with IM fibroids. TFD means the sum of the total reported fibroid diameters. SFD means the diameter of the largest single fibroid diameter. The ROC curve was generated based on the status of having a successful delivery or not. The AUC of the TFD curve is 0.610; 95% CI, 0.523– The AUC for the SFD is % CI, 0.514–0.688. Fertility and Sterility  , e6DOI: ( /j.fertnstert ) Copyright © 2014 American Society for Reproductive Medicine Terms and Conditions


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