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Władysław Sylwester Kopytowski (1858-1925): His life and early description of the microabscess in psoriasis  Andrzej Grzybowski, MD, PhD, Stefania Jabłońska,

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Presentation on theme: "Władysław Sylwester Kopytowski (1858-1925): His life and early description of the microabscess in psoriasis  Andrzej Grzybowski, MD, PhD, Stefania Jabłońska,"— Presentation transcript:

1 Władysław Sylwester Kopytowski ( ): His life and early description of the microabscess in psoriasis  Andrzej Grzybowski, MD, PhD, Stefania Jabłońska, MD, PhD  Clinics in Dermatology  Volume 29, Issue 1, Pages (January 2011) DOI: /j.clindermatol Copyright © Terms and Conditions

2 Fig. 1 Władysław Sylwester Kopytowski ( ). (Photo courtesy of the Polish Central Medical Library in Warsaw, Poland.) Clinics in Dermatology  , DOI: ( /j.clindermatol ) Copyright © Terms and Conditions

3 Fig. 2 Mature psoriasis: massive hyperkeratosis and parakeratosis, accumulation of leukocytes forming spongiform pustula, elongation of rete ridges, papillae with abundant leukocytes, and enlarged capillaries. Clinics in Dermatology  , DOI: ( /j.clindermatol ) Copyright © Terms and Conditions

4 Fig. 3 Mature psoriatic lesion with abundant hyperkeratosis and parakeratosis, leukocytes in the papillae (called squarting papilla), beneath stratum corneum a large space filled with fibrinoid. Clinics in Dermatology  , DOI: ( /j.clindermatol ) Copyright © Terms and Conditions

5 Fig. 4 The left panel shows elongated papilla with leukocytes penetrating squamous keratinocytes (squarting papilla). The right panel shows a hyperkeratotic psoriatic lesion. Clinics in Dermatology  , DOI: ( /j.clindermatol ) Copyright © Terms and Conditions

6 Fig. 5 The accumulation of leukocytes in dermal papillae, some of them somewhat elongated, with dilated capillaries. The granular layer is partly absent. Clinics in Dermatology  , DOI: ( /j.clindermatol ) Copyright © Terms and Conditions

7 Fig. 6 Munro microabscess: accumulation of leukocytes within stratum corneum, which is the most characteristic psoriatic papule in early psoriasis. The structure of the epidermis is still preserved, with no elongation of rete ridges. Clinics in Dermatology  , DOI: ( /j.clindermatol ) Copyright © Terms and Conditions


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