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Clinical Impact of Colonization with Multidrug-Resistant Organisms on Outcome after Autologous Stem Cell Transplantation: A Retrospective Single-Center.

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Presentation on theme: "Clinical Impact of Colonization with Multidrug-Resistant Organisms on Outcome after Autologous Stem Cell Transplantation: A Retrospective Single-Center."— Presentation transcript:

1 Clinical Impact of Colonization with Multidrug-Resistant Organisms on Outcome after Autologous Stem Cell Transplantation: A Retrospective Single-Center Study  Sebastian Scheich, Claudia Reinheimer, Christian Brandt, Thomas A. Wichelhaus, Michael Hogardt, Volkhard A.J. Kempf, Uta Brunnberg, Christian Brandts, Olivier Ballo, Ivana von Metzler, Johanna Kessel, Hubert Serve, Björn Steffen  Biology of Blood and Marrow Transplantation  Volume 23, Issue 9, Pages (September 2017) DOI: /j.bbmt Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

2 Figure 1 Kaplan-Meier estimates for overall survival (OS). (A) OS of all patients. (B) OS stratified by colonized (dotted line) and noncolonized (solid line) patients. (C) OS of patients with the diagnosis lymphoma stratified by colonized (dotted line) and noncolonized (solid line) patients. (D) OS of patients with the diagnosis myeloma stratified by colonized (dotted line) and noncolonized (solid line) patients. (E) OS of patients stratified by colonization with gram-positive (VRE, dotted line), gram-negative (dashed line), and noncolonized (solid line) patients. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

3 Figure 2 Incidence of nonrelapse mortality (NRM). (A) NRM for all patients. (B) NRM stratified by colonized (dotted line) and noncolonized (solid line) patients. (C) NRM of patients stratified by colonization with gram-positive (VRE, dotted line), gram-negative (dashed line), and noncolonized (solid line) patients. (D) NRM of patients with the diagnosis lymphoma stratified by colonization with gram-positive (VRE, dotted line), gram-negative (dashed line), and noncolonized (solid line) patients. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

4 Figure 3 Probability of progression. (A) Probability of progression of all patients (B) Probability of progression stratified by colonized (dotted line) and noncolonized (solid line) patients. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions


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