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Advances in Multiple Myeloma: Data Highlights and Analysis from the 2015 Hematology/Oncology Conferences.

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Presentation on theme: "Advances in Multiple Myeloma: Data Highlights and Analysis from the 2015 Hematology/Oncology Conferences."— Presentation transcript:

1 Advances in Multiple Myeloma: Data Highlights and Analysis from the 2015 Hematology/Oncology Conferences

2

3 Program Goals

4 Newly Diagnosed Multiple Myeloma

5 Current Approaches for Newly Diagnosed Multiple Myeloma (MM)

6 Importance of Fitness in Older Patients With MM

7 Future Directions in Treatment of Newly Diagnosed MM

8 Relapsed/Refractory Multiple Myeloma (R/R MM)

9 PANORAMA 1 Bortezomib/Dexamethasone ± Panobinostat

10 ASPIRE Carfilzomib, Lenalidomide, Dexamethasone (KRd) vs Len/Dex (Rd)

11 ENDEAVOR Carfilzomib/Dexamethasone (Kd) vs Bortezomib/Dexamethasone (Vd) in Patients With 1-3 Prior Lines of Therapy

12 Monoclonal Antibodies in Multiple Myeloma

13 ELOQUENT-2 Len/Dex ± Elotuzumab (anti-SLAMF7) in Relapsed/Refractory MM

14 SIRIUS Phase 2 Study of Daratumumab (anti-CD38) in Heavily Pretreated MM

15 Monoclonal Antibodies in MM Future Directions

16 New Targets in Multiple Myeloma

17 Novel Proteasome Inhibitors in Development

18 Novel Targeted Therapy Approaches in MM

19 Novel Approaches to MM Therapy

20 Biological Profiling of Multiple Myeloma

21 Current Role of Cytogenetics Prognostic Information

22 Measuring MRD in MM

23 MM is Heterogeneous in its Genetics

24 Summary Multiple Myeloma in 2015

25 Abbreviations

26 Abbreviations (cont)

27 Abbreviations (cont)

28 References

29 References (cont)

30 References (cont)

31 References (cont)

32 References (cont)

33 References (cont)

34 References (cont)

35 References (cont)

36 References (cont)

37 References (cont)

38 References (cont)

39 References (cont)

40 References (cont)


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