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Detection of Hodgkin lymphoma within ovarian tissue

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1 Detection of Hodgkin lymphoma within ovarian tissue
Sophie E. Bittinger, M.B., B.S., Simon P. Nazaretian, M.B., B.S., C.P.A., Debra A. Gook, Ph.D., Chandrika Parmar, M.D., Rosemary A. Harrup, M.B., B.S., Catharyn J. Stern, M.B., B.S.  Fertility and Sterility  Volume 95, Issue 2, Pages 803.e3-803.e6 (February 2011) DOI: /j.fertnstert Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions

2 Figure 1 (A) Laparoscopic view of ovary just before tissue harvest. (B) Normal ovarian cortex with scattered primordial follicles stained with hematoxylin and eosin (H & E; ×100). (C) Reactive lymphocytes and occasional atypical Hodgkin cells with large, irregular multilobated nuclei (arrow) and plump cytoplasm (H & E; ×200). (D) Neoplastic cells showing distinctive cell membrane and paranuclear dot staining positive for CD30 with immunoperoxidase (×200). (E) Scattered B lymphocytes staining positive for CD15 with immunoperoxidase, unstained small cells are reactive T lymphocytes (×200). (F) Neoplastic cells (arrow) showing no staining with CD20 immunoperoxidase (×400). Fertility and Sterility  , 803.e3-803.e6DOI: ( /j.fertnstert ) Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions


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