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A Tale of Division and Polarization in the Mammalian Embryo

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1 A Tale of Division and Polarization in the Mammalian Embryo
Shankar Srinivas, Tristan Argeo Rodriguez  Developmental Cell  Volume 40, Issue 3, Pages (February 2017) DOI: /j.devcel Copyright © Terms and Conditions

2 Figure 1 Importance of the Apical Domain for Inner Cell Mass versus Trophectoderm Lineage Segregation (A) Diagrammatic representation of the developmental stages of a mini-blastocyst. (B) Roles of the apical domain in TE specification. The apical domain is required to regulate the Hippo pathway in order to drive asymmetric cell division and to ensure that polarized cells remain on the outside of the embryo. Developmental Cell  , DOI: ( /j.devcel ) Copyright © Terms and Conditions


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