1. Cyclosporin A But Not FK-506 Protects Against Dopamine-Induced Apoptosis in the Stunned Heart 
Meena Nathan, MD, Ingeborg Friehs, MD, Yeong-Hoon Choi, MD, Douglas B. Cowan, PhD, Hung Cao-Danh, PhD, Francis X. McGowan, MD, Pedro J. del Nido, MD 
The Annals of Thoracic Surgery 
Volume 79, Issue 5, Pages (May 2005)
DOI: /j.athoracsur
Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

2. Fig 1
Systolic pressure, diastolic pressure, developed pressure and oxygen consumption, preischemia and postischemia. Data are mean ± standard error of the mean, *p < 0.05 versus dopamine, CSA+D, and FK+D. There was no significant difference between the three dopamine treated groups. (A) Change in systolic blood pressure; (B) change in diastolic blood pressure; (C) change in developed pressure; (D) change in oxygen consumption. ♦ = control; ■ = dopamine; ▴ = CSA+D; × = FK+D. (CSA+D = cyclosporin A + dopamine; FK+D = FK dopamine.)
The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur )
Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

3. Fig 2
Representative fluorescent and confocal photomicrographs of tissue sections, with terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL) positive nuclei in green, total nuclei in blue (4',6-diamidino-2-phenylindole [DAPI]), and cardiomyocytes stained red (Desmin). The numbers of TUNEL positive nuclei are expressed as n/1,000 total nuclei. Data are mean ± standard error of the mean, *p < 0.05 versus control; #p < 0.05 versus CSA+D. (A) TUNEL staining, fluorescent microscope; (B) TUNEL staining, confocal microscope; (C) quantitative data. ■ = control; ▤ = Dopa; □ = CSA+D; ▨ = FK+D. (CSA+D = cyclosporin A + dopamine; dopa = dopamine; FK+D = FK dopamine.)
The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur )
Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

4. Fig 3
Representative Western blots for Bax, active caspase-3 (from tissue extracts), and poly-ADP-ribose polymerase (PARP) (from nuclear extracts). Laser densitometry data are presented in the bar graph. Data are mean ± standard error of the mean, *p < 0.05 versus CSA+D. (A) Bax; (B) caspase-3; (C) PARP. ■ = control; ▤ = dopa; □ = CSA+D; ▨ = FK+D. (CSA+D = cyclosporin A + dopamine; dopa = dopamine; FK+D = FK dopamine.)
The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur )
Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions