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Volume 151, Issue 2, Pages e4 (August 2016)

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1 Volume 151, Issue 2, Pages 288-297.e4 (August 2016)
Rectal Indomethacin Reduces Pancreatitis in High- and Low-Risk Patients Undergoing Endoscopic Retrograde Cholangiopancreatography  Nikhil R. Thiruvengadam, Kimberly A. Forde, Gene K. Ma, Nuzhat Ahmad, Vinay Chandrasekhara, Gregory G. Ginsberg, Immanuel K. Ho, David Jaffe, Kashyap V. Panganamamula, Michael L. Kochman  Gastroenterology  Volume 151, Issue 2, Pages e4 (August 2016) DOI: /j.gastro Copyright © 2016 AGA Institute Terms and Conditions

2 Figure 1 (A) Chart comparing the percentage of patients with PEP in the indomethacin and unexposed groups overall, in patients with native papilla, and in patients who are post-sphincterotomy. (B) Chart comparing the percentage of patients who developed moderate-to-severe pancreatitis in the indomethacin and unexposed groups overall, in patients with native papilla and in patients who are post-sphincterotomy. Gastroenterology  , e4DOI: ( /j.gastro ) Copyright © 2016 AGA Institute Terms and Conditions

3 Figure 2 (A) A Forest plot displaying the OR of developing PEP comparing indomethacin with the unexposed group overall and in various subgroups. (B) A Forest plot displaying the OR of developing moderate-to-severe pancreatitis comparing indomethacin with the unexposed group overall and in various subgroups. In subgroups where there were no events or episodes of PEP, the OR was not pictured. Gastroenterology  , e4DOI: ( /j.gastro ) Copyright © 2016 AGA Institute Terms and Conditions

4 Figure 3 (A) Chart comparing the percentage of patients with malignant biliary obstruction who developed PEP in the indomethacin and unexposed groups overall, in patients with native papilla and in patients who are post-sphincterotomy. (B) Chart comparing the percentage of patients with malignant biliary obstruction who developed moderate-to-severe pancreatitis in the indomethacin and unexposed groups overall, in patients with native papilla and in patients who are post-sphincterotomy. Gastroenterology  , e4DOI: ( /j.gastro ) Copyright © 2016 AGA Institute Terms and Conditions

5 Figure 4 (A) A Forest plot displaying the OR of developing PEP in patients with malignant biliary obstruction comparing indomethacin with the unexposed group overall and in various subgroups. (B) A Forest plot displaying the OR of developed moderate-to-severe pancreatitis patients with malignant biliary obstruction comparing indomethacin with the unexposed group overall and in various subgroups. In subgroups, where there were no events or episodes of PEP, the OR was not pictured. Gastroenterology  , e4DOI: ( /j.gastro ) Copyright © 2016 AGA Institute Terms and Conditions

6 Supplementary Figure 1 (A) Propensity score histograms for indomethacin patients. (B) Propensity score histograms for unexposed patients. Gastroenterology  , e4DOI: ( /j.gastro ) Copyright © 2016 AGA Institute Terms and Conditions


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