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Which patients should be operated on after induction chemotherapy for N2 non–small cell lung cancer? Analysis of a 7-year experience in 175 patients 

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Presentation on theme: "Which patients should be operated on after induction chemotherapy for N2 non–small cell lung cancer? Analysis of a 7-year experience in 175 patients "— Presentation transcript:

1 Which patients should be operated on after induction chemotherapy for N2 non–small cell lung cancer? Analysis of a 7-year experience in 175 patients  Alessandro Stefani, MD, Marco Alifano, MD, Antonio Bobbio, MD, Madalina Grigoroiu, MD, Rami Jouni, MD, Pierre Magdeleinat, MD, Jean-Francois Regnard, MD  The Journal of Thoracic and Cardiovascular Surgery  Volume 140, Issue 2, Pages (August 2010) DOI: /j.jtcvs Copyright © 2010 The American Association for Thoracic Surgery Terms and Conditions

2 Figure 1 A, Survival by clinical response to chemotherapy. SD, Stable disease; OR, objective response. Five-year survival was 42% and 10% for responders and nonresponders, respectively. Median survival time was 50.8 and 19.0 months (P < .01). B, Survival by pathologic mediastinal downstaging. Five-year survival was 45% and 22% for patients with downstaged and persistent N2 disease, respectively. Median survival time was 50.9 and 24.9 months (P < .01). The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2010 The American Association for Thoracic Surgery Terms and Conditions


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