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Transplacental maternal engraftment and posttransplantation graft-versus-host disease in children with severe combined immunodeficiency  Justin Wahlstrom,

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Presentation on theme: "Transplacental maternal engraftment and posttransplantation graft-versus-host disease in children with severe combined immunodeficiency  Justin Wahlstrom,"— Presentation transcript:

1 Transplacental maternal engraftment and posttransplantation graft-versus-host disease in children with severe combined immunodeficiency  Justin Wahlstrom, MD, Kiran Patel, MD, Erik Eckhert, MS, Denice Kong, BS, Biljana Horn, MD, Morton J. Cowan, MD, Christopher C. Dvorak, MD  Journal of Allergy and Clinical Immunology  Volume 139, Issue 2, Pages e10 (February 2017) DOI: /j.jaci Copyright © Terms and Conditions

2 Fig 1 Incidence of aGVHD of any grade in patients with (solid line) and without (dashed line) TME. TME+ patients had a significantly higher risk of aGVHD (57.1% of patients) compared with TME− patients (17.9%, P = .0006). Journal of Allergy and Clinical Immunology  , e10DOI: ( /j.jaci ) Copyright © Terms and Conditions

3 Fig 2 Probability of overall survival in patients with (solid line) and without (dashed line) TME. Overall survival was defined as survival after transplantation. There was no statistically significant difference in overall survival between these patient groups. Journal of Allergy and Clinical Immunology  , e10DOI: ( /j.jaci ) Copyright © Terms and Conditions

4 Fig 3 Probability of event-free survival in patients with (solid line) and without (dashed line) TME. Event-free survival was defined as survival after transplantation without the need for additional (conditioned) transplant. There was no statistically significant difference in event-free survival between these patient groups. Journal of Allergy and Clinical Immunology  , e10DOI: ( /j.jaci ) Copyright © Terms and Conditions


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