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Kusum Lata, Rajesh Janardhanan  Journal of Indian College of Cardiology 

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Presentation on theme: "Kusum Lata, Rajesh Janardhanan  Journal of Indian College of Cardiology "— Presentation transcript:

1 A rare case of SVC syndrome: Accurate diagnosis by multi-modality imaging 
Kusum Lata, Rajesh Janardhanan  Journal of Indian College of Cardiology  Volume 4, Issue 2, Pages (June 2014) DOI: /j.jicc Copyright © Terms and Conditions

2 Fig. 1 Chest X-Ray showing a widened mediastinum.
Journal of Indian College of Cardiology 2014 4, DOI: ( /j.jicc ) Copyright © Terms and Conditions

3 Fig. 2 Chest CT, a large solid mass in the right hemithorax filling the right atrium. Journal of Indian College of Cardiology 2014 4, DOI: ( /j.jicc ) Copyright © Terms and Conditions

4 Fig. 3 Transthoracic echocardiogram, bulky mass in the right atrium.
Journal of Indian College of Cardiology 2014 4, DOI: ( /j.jicc ) Copyright © Terms and Conditions

5 Fig. 4 Cardiac MRI depicts mass infiltrating the superior vena cava and extending into the right atrium. Journal of Indian College of Cardiology 2014 4, DOI: ( /j.jicc ) Copyright © Terms and Conditions

6 Fig. 5 Cardiac MRI showing the tumor mass filling the right atrium.
Journal of Indian College of Cardiology 2014 4, DOI: ( /j.jicc ) Copyright © Terms and Conditions

7 Fig. 6 Histologic examination of the mediastinal mass reveals a diffuse proliferation of large atypical appearing CD20 and Pax 5 positive cells, indicating that these are B cells. The neoplastic cells are CD 10 negative and express BCL6 and MUM1 consistent with a post-germinal center phenotype. ALK 1 staining is negative. The morphologic features and immunophenotype are consistent with a diffuse large B cell lymphoma, post-germinal center B cell phenotype. Journal of Indian College of Cardiology 2014 4, DOI: ( /j.jicc ) Copyright © Terms and Conditions


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