1. Polymorphisms in Cytokine Genes Are Associated With Higher Levels of Fatigue and Lower Levels of Energy in Women After Breast Cancer Surgery 
Kord M. Kober, PhD, Betty Smoot, PT, DPTSc, Steven M. Paul, PhD, Bruce A. Cooper, PhD, Jon D. Levine, MD, PhD, Christine Miaskowski, RN, PhD 
Journal of Pain and Symptom Management 
Volume 52, Issue 5, Pages e4 (November 2016)
DOI: /j.jpainsymman
Copyright © 2016 American Academy of Hospice and Palliative Medicine Terms and Conditions

2. Fig. 1
Observed and estimated a) fatigue and b) energy trajectories for patients in each of the latent classes and the mean fatigue and energy scores for the total sample.
Journal of Pain and Symptom Management  , e4DOI: ( /j.jpainsymman )
Copyright © 2016 American Academy of Hospice and Palliative Medicine Terms and Conditions

3. Fig. 2
a) Differences between the fatigue latent classes in the percentages of patients who were homozygous or heterozygous for the common allele (GG + GA) or homozygous for the rare allele (AA) for rs16944 in interleukin 1 beta (IL1B). Values are plotted as unadjusted proportions with corresponding P-value. b) Differences between the fatigue latent classes in the percentages of patients who were homozygous or heterozygous for the common allele (TT + TC) or homozygous for the rare allele (CC) for rs in interleukin 10 (IL10). Values are plotted as unadjusted proportions with corresponding P-value.
Journal of Pain and Symptom Management  , e4DOI: ( /j.jpainsymman )
Copyright © 2016 American Academy of Hospice and Palliative Medicine Terms and Conditions

4. Fig. 3
Differences between the energy latent classes in the percentages of patients who were homozygous for the common allele (CC) or heterozygous or homozygous for the rare allele (CT + TT) for rss in interleukin 1 receptor 1 (IL1R1). Values are plotted as unadjusted proportions with corresponding P-value.
Journal of Pain and Symptom Management  , e4DOI: ( /j.jpainsymman )
Copyright © 2016 American Academy of Hospice and Palliative Medicine Terms and Conditions

5. Supplementary Fig. 1
Screenshot of the UCSC Genome Browser displaying a portion of the 3′ untranslated region of the IL1R1 gene on chromosome 2 of the hg19 (GRCh38) assembly. Assembly tracks show scale, scaffold and positions of the region, and gaps in the assembly. The gene model is provided by the “RefSeq Genes” track. The genomic loci of single-nucleotide polymorphism (SNP) rs in blue (annotated by dbSNP release 142) is shared with a CpG methylation site in orange (assayed by the Illumina HumanMethyl 450K bead array as part of the ENCODE project). This loci resides in a region flanked by SNP rs base pairs upstream and rs base pairs downstream. SNP loci for which population data is available from the 1000 Genomes project are identified in the “1000 Genomes Phase 1 Integrated Variant Calls” track in black.
Journal of Pain and Symptom Management  , e4DOI: ( /j.jpainsymman )
Copyright © 2016 American Academy of Hospice and Palliative Medicine Terms and Conditions