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A method of determining the existence of bursting solutions, and output variables such as burst length and spike number, of multidimensional models using.

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Presentation on theme: "A method of determining the existence of bursting solutions, and output variables such as burst length and spike number, of multidimensional models using."— Presentation transcript:

1 A method of determining the existence of bursting solutions, and output variables such as burst length and spike number, of multidimensional models using mapping.

2 The Model

3 T-current mechanism for escape

4 Release of Synaptic inhibition

5 Mapping Fixed points of mark out-of-phase bursting

6

7 A function of T-current inactivation parameters alone

8

9 Stability has to be determined numerically

10 Parameter sensitivity analysis
depends on but does not depends on but does not

11 Relaxing the assumptions
Half-center bursting: T-current inactivation threshold lies just beneath spiking threshold Synaptic decay faster than spiking dynamics Relaxing the half-center assumptions means that has to be calculated numerically, and becomes discontinuous. Nevertheless, the number of stable solutions increases.


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