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Natural History of Potential Celiac Disease in Children

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Presentation on theme: "Natural History of Potential Celiac Disease in Children"— Presentation transcript:

1 Natural History of Potential Celiac Disease in Children
Antonella Tosco, Virginia Michela Salvati, Renata Auricchio, Mariantonia Maglio, Melissa Borrelli, Anna Coruzzo, Francesco Paparo, Massimo Boffardi, Antonella Esposito, Grazia D'Adamo, Basilio Malamisura, Luigi Greco, Riccardo Troncone  Clinical Gastroenterology and Hepatology  Volume 9, Issue 4, Pages (April 2011) DOI: /j.cgh Copyright © 2011 AGA Institute Terms and Conditions

2 Figure 1 (A–C) Detection of IgA deposits in duodenal mucosa from a potential CD patient. TG2 (in red) shows a subepithelial localization (B), IgA in green (C) are present inside plasma cells; thin layers of anti-TG2 antibody mucosal deposits are visible in subepithelial areas. In panel A, yellow color indicates colocalization of IgA anti-TG2 mucosal deposits and TG2. (D–F) Duodenal mucosa from a potential CD patient negative for deposits of IgA anti-TG2. IgA are visible, in green, only inside plasma cells and epithelial cells (F), TG2 in red presents a subepithelial distribution (E). No area of colocalization is evident (D). Clinical Gastroenterology and Hepatology 2011 9, DOI: ( /j.cgh ) Copyright © 2011 AGA Institute Terms and Conditions

3 Figure 2 Study population.
Clinical Gastroenterology and Hepatology 2011 9, DOI: ( /j.cgh ) Copyright © 2011 AGA Institute Terms and Conditions


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