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Genetic Linkage Analysis of a Dichotomous Trait Incorporating a Tightly Linked Quantitative Trait in Affected Sib Pairs  Jian Huang, Yanming Jiang  The.

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Presentation on theme: "Genetic Linkage Analysis of a Dichotomous Trait Incorporating a Tightly Linked Quantitative Trait in Affected Sib Pairs  Jian Huang, Yanming Jiang  The."— Presentation transcript:

1 Genetic Linkage Analysis of a Dichotomous Trait Incorporating a Tightly Linked Quantitative Trait in Affected Sib Pairs  Jian Huang, Yanming Jiang  The American Journal of Human Genetics  Volume 72, Issue 4, Pages (April 2003) DOI: /374568 Copyright © 2003 The American Society of Human Genetics Terms and Conditions

2 Figure 1 Histograms of total IgE level and its transformations. The Y-axis in each panel represents density. a, Standardized total IgE levels. b, Standardized logarithm of total IgE levels. c, Standardized square root of total IgE levels. d, Transformed total IgE levels. The American Journal of Human Genetics  , DOI: ( /374568) Copyright © 2003 The American Society of Human Genetics Terms and Conditions

3 Figure 2 LOD scores on chromosomes 1–12. Solid line = CLR; dotted line = MLS; dashed line = H-E The American Journal of Human Genetics  , DOI: ( /374568) Copyright © 2003 The American Society of Human Genetics Terms and Conditions

4 Figure 3 LOD scores on chromosomes 13–22. Solid line = CLR; dotted line = MLS; dashed line = H-E The American Journal of Human Genetics  , DOI: ( /374568) Copyright © 2003 The American Society of Human Genetics Terms and Conditions


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