1. Effect of ventilation on cerebral oxygenation in patients undergoing surgery in the beach chair position: a randomized controlled trial 
G.S. Murphy, J.W. Szokol, M.J. Avram, S.B. Greenberg, T.D. Shear, J.S. Vender, S.D. Levin, J.L. Koh, K.N. Parikh, S.S. Patel 
British Journal of Anaesthesia 
Volume 113, Issue 4, Pages (October 2014)
DOI: /bja/aeu109
Copyright © 2014 The Author(s) Terms and Conditions

2. Fig 1
CONSORT trial flow diagram for the study of the effect of ventilation on cerebral oxygenation in patients undergoing surgery in the BCP.
British Journal of Anaesthesia  , DOI: ( /bja/aeu109)
Copyright © 2014 The Author(s) Terms and Conditions

3. Fig 2
End-tidal sevoflurane concentrations (e′Sevo, %) for the patients in the control (end-tidal carbon dioxide=30–32 mm Hg) group and in the study (end-tidal carbon dioxide=40–42 mm Hg) group. The data are presented as mean (sd). Time is minutes after induction of anaesthesia, with immediate post-induction measurements presented at time 0 min. The asterisk indicates the time at which the e′Sevo in the patients in the control group differed from their baseline e′Sevo (42 min, P<0.01). The e′Sevo in the patients in the study group did not differ from their baseline e′Sevo and there were no difference in e′Sevo between patients of the study group and those of the control group. The numbers of patients in the control group and in the study group were 36 and 32, respectively, at baseline and were 33 and 32 in the two groups at 56 min, respectively.
British Journal of Anaesthesia  , DOI: ( /bja/aeu109)
Copyright © 2014 The Author(s) Terms and Conditions

4. Fig 3
End-tidal carbon dioxide concentration ( E C O 2 ′ ) (mm Hg) for the patients in the control (end-tidal carbon dioxide=30–32 mm Hg) group and in the study (end-tidal carbon dioxide=40–42 mm Hg) group. The data are presented as mean (sd). Time is minutes after induction of anaesthesia, with immediate post-induction measurements presented at time 0 min. The solid horizontal line indicates the time during which the E C O 2 ′ in the patients in the control group differed from their baseline HRs (6, 20, 28–40, 52–60 min, overall P<0.01), while the dotted horizontal line indicates the time during which the E C O 2 ′ in the patients in the study group differed from their baseline HRs (4–60 min, overall P<0.01). The dashed horizontal line indicates the times during which the E C O 2 ′ in the patients of the study group differed from those in the control group (0–60 min, overall P<0.01). The numbers of patients in the control group and in the study group were 36 and 34, respectively, at baseline and decreased to 31 in both groups at 60 min.
British Journal of Anaesthesia  , DOI: ( /bja/aeu109)
Copyright © 2014 The Author(s) Terms and Conditions

5. Fig 4
HR (beats min−1) for the patients in the control (end-tidal carbon dioxide=30–32 mm Hg) group and in the study (end-tidal carbon dioxide=40–42 mm Hg) group. The data are presented as mean (sd). Time is minutes since induction of anaesthesia, with preinduction baseline measurements presented at time 0 min. The solid horizontal line indicates the time during which the HRs in the patients in the control group differed from their baseline HRs (44, 50–52, 58–60 min, overall P<0.01), while the dotted horizontal line indicates the time during which the HRs in the patients in the study group differed from their baseline HRs (44–46, 52–60 min, overall P<0.01). There were no differences between the groups at any time. The numbers of patients in the control group and in the study group were 36 and 34, respectively, at baseline and decreased to 31 in both groups at 60 min.
British Journal of Anaesthesia  , DOI: ( /bja/aeu109)
Copyright © 2014 The Author(s) Terms and Conditions

6. Fig 5
MAP (mm Hg) for the patients in the control (end-tidal carbon dioxide=30–32 mm Hg) group and in the study (end-tidal carbon dioxide=40–42 mm Hg) group. The data are presented as mean (sd). Time is minutes since induction of anaesthesia, with preinduction baseline measurements presented at time 0 min. The solid horizontal line indicates the time during which the MAPs in the patients in the control group differed from their baseline MAPs (16–20, 40–44, and 48–50 min, overall P<0.01), while the dotted horizontal line indicates the time during which the MAPs in the patients in the study group differed from their baseline MAPs (14–18, 42–48, and 56 min, overall P<0.01). There were no differences between the groups at any time. The numbers of patients in the control group and in the study group were 36 and 34, respectively, at baseline and decreased to 31 in both groups at 60 min.
British Journal of Anaesthesia  , DOI: ( /bja/aeu109)
Copyright © 2014 The Author(s) Terms and Conditions

7. Fig 6
Regional cerebral oxygen saturation ( S c t O 2 ) for the patients in the control (end-tidal carbon dioxide=30–32 mm Hg) group and in the study (end-tidal carbon dioxide=40–42 mm Hg) group. The data are presented as mean (sd). Time is minutes since induction of anaesthesia, with preinduction baseline measurements presented at time 0 min. The solid horizontal line indicates the time during which the S c t O 2 s in the patients of the control group differed from their baseline S c t O 2 s (10–60 min, overall P<0.01). The dashed horizontal line indicates the times during which the S c t O 2 s in the patients of the study group differed from those in the control group (16–60 min, overall P<0.01). The numbers of patients in the control group and in the study group were 36 and 34, respectively, at baseline and decreased to 31 in both groups at 60 min.
British Journal of Anaesthesia  , DOI: ( /bja/aeu109)
Copyright © 2014 The Author(s) Terms and Conditions