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Hematopoiesis Lineage Tree Uprooted: Every Cell Is a Rainbow

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Presentation on theme: "Hematopoiesis Lineage Tree Uprooted: Every Cell Is a Rainbow"— Presentation transcript:

1 Hematopoiesis Lineage Tree Uprooted: Every Cell Is a Rainbow
Karen K. Hirschi, Stefania Nicoli, Kenneth Walsh  Developmental Cell  Volume 41, Issue 1, Pages 7-9 (April 2017) DOI: /j.devcel Copyright © 2017 Elsevier Inc. Terms and Conditions

2 Figure 1 Generic Models of Lineage Commitment
(A) Lineage tree model: The most oligo-potent cell is depicted in white, and transitions via binary fate decisions to ultimately generate distinct cell lineages are depicted in vibrant, distinct colors. (B) Lineage continuum model: All oligo-potent cells are highly transcriptionally diverse and undergo direct lineage commitment to generate distinct cell types, as opposed to transitioning through a series of discrete and stable progenitors. Developmental Cell  , 7-9DOI: ( /j.devcel ) Copyright © 2017 Elsevier Inc. Terms and Conditions

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